Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | TSHR | P16473 | 4/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | CRHBP | P24387 | 1/20 | 0.53 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.49 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.49 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29106573 | 0.86 | ALDH1A1 (0.47) | ALDH1A1TSHRTDP1CYP3A4LMNA | |
| SCHEMBL28092025 | 0.83 | CHRNB4 (0.67) | ALDH1A1TSHRTDP1LMNAHSP90AA1 | |
| SCHEMBL15822165 | 0.83 | ALDH1A1 (0.49) | ALDH1A1TSHRTDP1CYP3A4LMNA | |
| SCHEMBL10811831 | 0.82 | ALDH1A1 (0.50) | ALDH1A1TSHRTDP1CYP3A4LMNA | |
| SCHEMBL27988565 | 0.79 | ALDH1A1 (0.55) | ALDH1A1TSHRTDP1CYP3A4LMNA | |
| SCHEMBL25886876 | 0.79 | HSP90AA1 (0.51) | ALDH1A1TSHRTDP1LMNAHSP90AA1 | |
| SCHEMBL28164210 | 0.79 | HSD17B10 (0.58) | ALDH1A1TSHRTDP1LMNAMAPT | |
| SCHEMBL430993 | 0.79 | CYP3A4 (0.53) | ALDH1A1TSHRTDP1CYP3A4LMNA | |
| SCHEMBL6608231 | 0.79 | HSP90AA1 (0.51) | ALDH1A1TSHRTDP1CYP3A4LMNA | |
| SCHEMBL28164239 | 0.77 | HSD17B10 (0.56) | ALDH1A1TSHRTDP1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1448536-A1 | CYCLOPROPYL-CONTAINING OXAZOLIDINONE ANTIBIOTICS AND DERIVATIVES THEREOF | Merck & Co., Inc. (US) | 2004-08-25 | — | — | EP | disclosed |
| WO-2003048136-A1 | CYCLOPROPYL HEXANE CONTAINING OXAZOLIDINONE ANTIBIOTICS AND DERIVATIVES THEREOF | MERCK & CO., INC. (US) | 2003-06-12 | — | — | WO | disclosed |