Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
| ▸ | CCR8 | P51685 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.38 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6609228 | 1.00 | GRM2 (0.42) | GRM2ALDH1A1NPC1CYP2D6CYP2C19 | |
| SCHEMBL6608831 | 1.00 | GRM2 (0.42) | GRM2ALDH1A1NPC1CYP2D6CYP2C19 | |
| SCHEMBL6611157 | 1.00 | GRM2 (0.42) | GRM2ALDH1A1NPC1CYP2D6CYP2C19 | |
| SCHEMBL6603081 | 0.98 | GRM2 (0.43) | GRM2ALDH1A1NPC1CYP2D6CYP2C19 | |
| SCHEMBL4495520 | 0.92 | ALDH1A1 (0.42) | GRM2ALDH1A1NPC1CYP2D6CYP2C19 | |
| SCHEMBL2416582 | 0.86 | ALDH1A1 (0.50) | GRM2ALDH1A1NPC1CYP2D6CYP2C19 | |
| SCHEMBL30402955 | 0.86 | ALDH1A1 (0.50) | GRM2ALDH1A1NPC1CYP2D6CYP2C19 | |
| SCHEMBL4190714 | 0.81 | KDM4E (0.50) | ALDH1A1NPC1CYP2D6CYP2C19KDM4E | |
| SCHEMBL4885285 | 0.81 | SOAT1 (0.49) | ALDH1A1NPC1CYP2D6CYP2C19KDM4E | |
| SCHEMBL21494430 | 0.81 | SOAT1 (0.49) | ALDH1A1NPC1CYP2D6CYP2C19KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6787561-B1 | HYPERLIPIDEMIA, ARTERIOSCLEROSIS; ORAL ADMINISTRATION; SUPPRESSING THE FORMING OF MACROPHAGES | FUJI PHOTO FILM CO., LTD. (JP) | 2004-09-07 | — | — | US | disclosed |
| EP-1197493-B1 | BENZIMIDAZOLE COMPOUNDS | FUJI PHOTO FILM CO LTD (JP) | 2004-03-24 | — | — | EP | disclosed |
| EP-1197493-A1 | BENZIMIDAZOLE COMPOUNDS | FUJI PHOTO FILM CO., LTD. (JP) | 2002-04-17 | — | — | EP | disclosed |