Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 8/20 | 0.59 |
| ▸ | WNT3A | P56704 | 8/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 2/20 | 0.38 |
| ▸ | EPM2A | O95278 | 1/20 | 0.38 |
| ▸ | PTPRC | P08575 | 1/20 | 0.38 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.38 |
| ▸ | CDC14A | Q9UNH5 | 1/20 | 0.38 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31122367 | 0.80 | HTT (0.53) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL1128514 | 0.80 | HTT (0.53) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL824471 | 0.75 | ALDH1A1 (0.66) | ALDH1A1HPGDPOLBALOX15MAPK1 | |
| SCHEMBL15968867 | 0.75 | CTNNB1 (1.00) | CTNNB1WNT3AIDO1RAB9AHTR1B | |
| SCHEMBL15941192 | 0.75 | CTNNB1 (0.83) | CTNNB1WNT3AMRGPRX4HPGDALOX15 | |
| SCHEMBL1127787 | 0.72 | ALDH1A1 (0.58) | ALDH1A1HPGDPOLBALOX15MAPK1 | |
| Formaldehyde SCHEMBL28198922 | 0.72 | ALDH1A1 (0.61) | ALDH1A1HPGDPOLBALOX15MAPK1 | |
| SCHEMBL8014833 | 0.71 | ALDH1A1 (0.56) | ALDH1A1HPGDPOLBHSD17B10KMT2A | |
| SCHEMBL9787242 | 0.71 | ALDH1A1 (0.61) | ALDH1A1HPGDPOLBALOX15MAPK1 | |
| SCHEMBL5970917 | 0.71 | HDAC3 (0.58) | ALDH1A1HPGDPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289980-B1 | BICYCLYL OR HETEROBICYCLYLMETHANESULFONYLAMINO-SUBSTITUTED N-HYDROXYFORMAMIDES | SMITHKLINE BEECHAM PLC (GB) | 2004-11-17 | — | — | EP | disclosed |
| EP-1289980-A1 | BICYCLYL OR HETEROBICYCLYLMETHANESULFONYLAMINO-SUBSTITUTED N-HYDROXYFORMAMIDES | SMITHKLINE BEECHAM PLC (GB) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001090100-A1 | BICYCLYL OR HETEROBICYCLYLMETHANESULFONYLAMINO-SUBSTITUTED N-HYDROXYFORMAMIDES | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-11-29 | — | — | WO | disclosed |