Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | IRS1 | P35568 | 1/20 | 0.32 |
| ▸ | GAB1 | Q13480 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6596749 | 0.87 | GPBAR1 (0.36) | GPBAR1F10NR1H4PPARGPPARD | |
| SCHEMBL6607062 | 0.85 | GPBAR1 (0.34) | GPBAR1F10 | |
| SCHEMBL8762913 | 0.80 | SMURF2 (0.38) | GPBAR1F10NR1H4PPARGPPARD | |
| SCHEMBL28600495 | 0.79 | GPBAR1 (0.44) | GPBAR1F10NR1H4PPARGPPARD | |
| SCHEMBL8488379 | 0.79 | HTT (0.38) | PPARGPPARDPPARA | |
| SCHEMBL8493346 | 0.78 | NR1H4 (0.38) | GPBAR1F10NR1H4PPARGPPARD | |
| SCHEMBL9116239 | 0.76 | NR1H4 (0.35) | GPBAR1F10NR1H4PPARGPPARD | |
| SCHEMBL123795 | 0.74 | F10 (0.39) | F10SLC6A9 | |
| SCHEMBL4894785 | 0.74 | F10 (0.39) | F10SLC6A9 | |
| SCHEMBL6054858 | 0.73 | CACNA1B (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0901479-B1 | ISOXAZOLE DERIVATIVES AND THEIR USE AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2004-02-11 | — | — | EP | claimed |