Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMURF2 | Q9HAU4 | 1/20 | 0.38 |
| ▸ | SMURF1 | Q9HCE7 | 1/20 | 0.38 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 8/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | FABP4 | P15090 | 1/20 | 0.32 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8493346 | 0.89 | NR1H4 (0.38) | GPBAR1PPARGPPARDPPARAF10 | |
| SCHEMBL8762917 | 0.87 | WDR5 (0.37) | SMURF2SMURF1NR1H4 | |
| SCHEMBL8488379 | 0.86 | HTT (0.38) | PPARGPPARDPPARANPC1 | |
| SCHEMBL9116239 | 0.86 | NR1H4 (0.35) | GPBAR1PPARGPPARDPPARAF10 | |
| SCHEMBL8762928 | 0.86 | SMURF2 (0.36) | SMURF2SMURF1GPBAR1NR1H4 | |
| SCHEMBL6054814 | 0.85 | CACNA1B (0.40) | NR1H4PTGDR2 | |
| SCHEMBL8763780 | 0.84 | BCAT2 (0.39) | SMURF2SMURF1GPBAR1STAT3NPC1 | |
| SCHEMBL6596749 | 0.84 | GPBAR1 (0.36) | GPBAR1PPARGPPARDPPARAF10 | |
| SCHEMBL28600495 | 0.84 | GPBAR1 (0.44) | GPBAR1PPARGPPARDPPARAF10 | |
| SCHEMBL8634180 | 0.84 | GPBAR1 (0.38) | SMURF2SMURF1GPBAR1PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1040940-C | Composition containing 4-benzoyl isoxazole derivative and application thereof | RHONE POULENE AGRICULTURE LTD (GB) | 1998-12-02 | — | — | CN | claimed |
| EP-0487357-B1 | 4 Benzoyl isoxazole derivatives | RHONE POULENC AGRICULTURE (GB) | 1997-07-02 | — | — | EP | claimed |
| CN-1061596-A | 4-Benzoylisoxazole Derivatives | RHONE POULENC AGRICULTURE (GB) | 1992-06-03 | — | — | CN | claimed |
| CN-1093537-C | Process for preparing composition contg. 4 -benzoyl-iso-oxazole derivs. | PHONE POULENC AGRICULTURE LTD (GB) | 2002-10-30 | — | — | CN | disclosed |
| CN-1040940-C | Composition containing 4-benzoyl isoxazole derivative and application thereof | RHONE POULENE AGRICULTURE LTD (GB) | 1998-12-02 | — | — | CN | disclosed |
| CN-1183411-A | Process for preparing composition contg. 4 -benzoyl-iso-oxazole derivs. | RHONE POULENC AGRICULTURE (GB) | 1998-06-03 | — | — | CN | disclosed |
| CN-1061596-A | 4-Benzoylisoxazole Derivatives | RHONE POULENC AGRICULTURE (GB) | 1992-06-03 | — | — | CN | disclosed |