Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | FCER2 | P06734 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | ACP1 | P24666 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6607278 | 1.00 | CYP1A2 (0.42) | CYP1A2MMP9MMP2MMP8RAB9A | |
| SCHEMBL6403781 | 0.91 | CYP1A2 (0.36) | CYP1A2MMP9MMP2MMP8RAB9A | |
| SCHEMBL6611578 | 0.91 | CYP1A2 (0.41) | CYP1A2MMP9MMP2MMP8RAB9A | |
| SCHEMBL6611575 | 0.91 | CYP1A2 (0.41) | CYP1A2MMP9MMP2MMP8RAB9A | |
| SCHEMBL6401254 | 0.89 | CYP1A2 (0.35) | CYP1A2MMP9MMP2MMP8RAB9A | |
| SCHEMBL6608596 | 0.88 | KMT2A (0.41) | CYP1A2MMP9MMP2MMP8RAB9A | |
| SCHEMBL6608597 | 0.88 | KMT2A (0.41) | CYP1A2MMP9MMP2MMP8RAB9A | |
| SCHEMBL6608483 | 0.88 | MMP2 (0.45) | CYP1A2MMP9MMP2MMP8RAB9A | |
| SCHEMBL6608479 | 0.88 | MMP2 (0.45) | CYP1A2MMP9MMP2MMP8RAB9A | |
| SCHEMBL6604910 | 0.85 | HPGD (0.46) | CYP1A2MMP9MMP2MMP8RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289980-B1 | BICYCLYL OR HETEROBICYCLYLMETHANESULFONYLAMINO-SUBSTITUTED N-HYDROXYFORMAMIDES | SMITHKLINE BEECHAM PLC (GB) | 2004-11-17 | — | — | EP | disclosed |