Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 10/20 | 0.61 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | ESRRG | P62508 | 2/20 | 0.61 |
| ▸ | AR | P10275 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.61 |
| ▸ | HTR6 | P50406 | 1/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TYR | P14679 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30625965 | 1.00 | ESR1 (0.61) | ESR1ESR2HSD17B10CYP3A4HPGD | |
| SCHEMBL16565722 | 1.00 | ESR1 (0.61) | ESR1ESR2HSD17B10CYP3A4HPGD | |
| SCHEMBL15961422 | 0.95 | ESR1 (0.55) | ESR1ESR2HSD17B10CYP3A4HPGD | |
| SCHEMBL4462227 | 0.94 | ESR1 (0.59) | ESR1ESR2HSD17B10CYP3A4HPGD | |
| SCHEMBL29372911 | 0.92 | ESR1 (0.61) | ESR1ESR2HSD17B10CYP3A4HPGD | |
| SCHEMBL544510 | 0.92 | ESR1 (0.61) | ESR1ESR2HSD17B10CYP3A4HPGD | |
| Cyanate SCHEMBL30541970 | 0.92 | ESR1 (0.52) | ESR1ESR2HSD17B10CYP3A4HPGD | |
| SCHEMBL12299320 | 0.89 | ESR1 (0.49) | ESR1ESR2HSD17B10CYP3A4HPGD | |
| SCHEMBL4460477 | 0.85 | ESR1 (0.60) | ESR1ESR2HSD17B10CYP3A4HPGD | |
| SCHEMBL17456366 | 0.85 | ESR1 (0.77) | ESR1ESR2HSD17B10CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1375463-A1 | OPTICALLY ACTIVE COMPOUND AND PHOTOSENSITIVE RESIN COMPOSITION | Kansai Research Institute, Inc. (JP) | 2004-01-02 | — | — | EP | disclosed |