Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR1 | P47211 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | TPH1 | P17752 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5554034 | 0.99 | GALR1 (0.38) | GALR1MAPK1TLR7HTR2AHTR2C | |
| SCHEMBL6428528 | 0.97 | GALR1 (0.35) | GALR1MAPK1DHFR | |
| SCHEMBL5553495 | 0.93 | MAPK1 (0.34) | GALR1MAPK1 | |
| SCHEMBL5553512 | 0.93 | MAPK1 (0.39) | GALR1MAPK1 | |
| SCHEMBL6427958 | 0.93 | GALR1 (0.33) | GALR1TLR7TPH1ADORA2AADORA1 | |
| SCHEMBL6429776 | 0.92 | ADRA2A (0.33) | GALR1TPH1ADORA2AADORA1 | |
| SCHEMBL6429682 | 0.91 | MAPK1 (0.32) | GALR1MAPK1 | |
| SCHEMBL6231925 | 0.91 | TLR7 (0.34) | GALR1TLR7TPH1SMN1; SMN2MEN1 | |
| SCHEMBL6428224 | 0.90 | CCNK (0.33) | GALR1MAPK1ADORA2AADORA1 | |
| SCHEMBL6016949 | 0.89 | SMN1; SMN2 (0.43) | GALR1MAPK1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1436266-A4 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | REDDY US THERAPEUTICS INC (US) | 2004-12-22 | — | — | EP | claimed |
| EP-1436266-A2 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | Reddy US Therapeutics, Inc. (US) | 2004-07-14 | — | — | EP | claimed |
| WO-2003024926-A2 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | REDDY US THERAPEUTICS, INC. (US) | 2003-03-27 | — | — | WO | claimed |