Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 20/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6607279 | 0.84 | GRM2 (0.53) | GRM2 | |
| SCHEMBL7082493 | 0.83 | GRM2 (0.48) | GRM2 | |
| SCHEMBL7082491 | 0.83 | GRM2 (0.48) | GRM2 | |
| SCHEMBL11069385 | 0.80 | GRM2 (0.52) | GRM2 | |
| SCHEMBL7164286 | 0.80 | GRM2 (0.47) | GRM2 | |
| SCHEMBL7164281 | 0.80 | GRM2 (0.47) | GRM2 | |
| SCHEMBL5235122 | 0.76 | GRM2 (0.47) | GRM2 | |
| SCHEMBL6211849 | 0.76 | GRM2 (0.46) | GRM2 | |
| SCHEMBL6211853 | 0.76 | GRM2 (0.46) | GRM2 | |
| SCHEMBL2411700 | 0.76 | HDAC1 (0.48) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1082322-B1 | OXAZOLIDINONE DERIVATIVES AS ANTIBIOTIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ASTRAZENECA AB (SE) | 2004-01-28 | — | — | EP | disclosed |
| EP-1357122-A2 | Oxazolidinone compounds and pharmaceutical compositions containing them | AstraZeneca AB (SE) | 2003-10-29 | — | — | EP | disclosed |