Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 19/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6607413 | 0.84 | GRM2 (0.54) | GRM2 | |
| SCHEMBL2411700 | 0.83 | HDAC1 (0.48) | GRM2 | |
| SCHEMBL5425956 | 0.80 | GRM2 (0.52) | GRM2 | |
| SCHEMBL5425950 | 0.80 | GRM2 (0.52) | GRM2 | |
| SCHEMBL8114760 | 0.79 | GRM2 (0.63) | GRM2 | |
| SCHEMBL8114758 | 0.79 | GRM2 (0.63) | GRM2 | |
| SCHEMBL2823408 | 0.77 | GRM2 (0.59) | GRM2 | |
| SCHEMBL7300463 | 0.77 | GRM2 (0.49) | GRM2 | |
| SCHEMBL6613015 | 0.76 | MAOA (0.58) | GRM2 | |
| SCHEMBL6613011 | 0.76 | MAOA (0.58) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1082322-B1 | OXAZOLIDINONE DERIVATIVES AS ANTIBIOTIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ASTRAZENECA AB (SE) | 2004-01-28 | — | — | EP | disclosed |
| EP-1357122-A2 | Oxazolidinone compounds and pharmaceutical compositions containing them | AstraZeneca AB (SE) | 2003-10-29 | — | — | EP | disclosed |