Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 11/20 | 0.39 |
| ▸ | PDE4A | P27815 | 7/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 7/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 7/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6607423 | 1.00 | KDM4E (0.40) | KDM4EMAPTALDH1A1NPSR1MEN1 | |
| SCHEMBL6611092 | 0.91 | PDE4D (0.43) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL6611085 | 0.91 | PDE4D (0.43) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL6610551 | 0.82 | PDE4D (0.43) | KDM4EMAPTALDH1A1NPSR1MEN1 | |
| SCHEMBL6610555 | 0.82 | PDE4D (0.43) | KDM4EMAPTALDH1A1NPSR1MEN1 | |
| SCHEMBL6606084 | 0.81 | MAPT (0.39) | KDM4EMAPTALDH1A1NPSR1MEN1 | |
| SCHEMBL6606089 | 0.81 | MAPT (0.39) | KDM4EMAPTALDH1A1NPSR1MEN1 | |
| SCHEMBL6606520 | 0.81 | PDE4B (0.42) | KDM4EMAPTALDH1A1NPSR1MEN1 | |
| SCHEMBL6606526 | 0.81 | PDE4B (0.42) | KDM4EMAPTALDH1A1NPSR1MEN1 | |
| SCHEMBL6609810 | 0.80 | KDM4E (0.52) | KDM4EMAPTALDH1A1NPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882714-B1 | SUBSTITUTED VINYLPYRIDINE DERIVATIVES AND DRUGS CONTAINING THE SAME | SS PHARMACEUTICAL CO (JP) | 2004-03-03 | — | — | EP | disclosed |
| US-5935977-A | PHOSPHODIESTERASE IV INHIBITORS, TUMOR NECROSIS FACTOR-ALPHA PRODUCTION INHIBITORS; TREATING INFLAMMATORY AND AUTOIMMUNE DISEASES | SS PHARMACEUTICAL CO., LTD. (JP) | 1999-08-10 | — | — | US | disclosed |
| EP-0882714-A1 | SUBSTITUTED VINYLPYRIDINE DERIVATIVES AND DRUGS CONTAINING THE SAME | SS Pharmaceutical Co., Ltd. (JP) | 1998-12-09 | — | — | EP | disclosed |