Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 14/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 17/20 | 0.41 |
| ▸ | PDE4A | P27815 | 12/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 12/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6611092 | 1.00 | PDE4D (0.43) | PDE4DPDE4BPDE4APDE4CFFAR4 | |
| SCHEMBL6607425 | 0.91 | KDM4E (0.40) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL6607423 | 0.91 | KDM4E (0.40) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL6608418 | 0.89 | CHEK1 (0.35) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL6605174 | 0.89 | CHEK1 (0.35) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL6609898 | 0.88 | PDE4D (0.44) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL6609891 | 0.88 | PDE4D (0.44) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL6606520 | 0.87 | PDE4B (0.42) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL6606526 | 0.87 | PDE4B (0.42) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL6606787 | 0.83 | PDE4D (0.42) | PDE4DPDE4BPDE4APDE4CFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882714-B1 | SUBSTITUTED VINYLPYRIDINE DERIVATIVES AND DRUGS CONTAINING THE SAME | SS PHARMACEUTICAL CO (JP) | 2004-03-03 | — | — | EP | disclosed |
| US-5935977-A | PHOSPHODIESTERASE IV INHIBITORS, TUMOR NECROSIS FACTOR-ALPHA PRODUCTION INHIBITORS; TREATING INFLAMMATORY AND AUTOIMMUNE DISEASES | SS PHARMACEUTICAL CO., LTD. (JP) | 1999-08-10 | — | — | US | disclosed |
| EP-0882714-A1 | SUBSTITUTED VINYLPYRIDINE DERIVATIVES AND DRUGS CONTAINING THE SAME | SS Pharmaceutical Co., Ltd. (JP) | 1998-12-09 | — | — | EP | disclosed |