Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | ACHE | P22303 | 17/20 | 0.65 |
| ▸ | BCHE | P06276 | 12/20 | 0.65 |
| ▸ | GRIN1 | Q05586 | 6/20 | 0.65 |
| ▸ | GRIN2A | Q12879 | 6/20 | 0.65 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6610603 | 0.84 | ACHE (0.66) | MAPTACHEBCHEGRIN1GRIN2A | |
| SCHEMBL6608783 | 0.81 | ACHE (0.68) | ACHEBCHEGRIN1GRIN2ACHRM1 | |
| SCHEMBL6611810 | 0.81 | MAPT (0.97) | MAPTACHEBCHEGRIN1GRIN2A | |
| SCHEMBL6609348 | 0.81 | MAPT (0.61) | MAPTACHEBCHEGRIN1GRIN2A | |
| SCHEMBL6610838 | 0.81 | ACHE (0.62) | MAPTACHEBCHEGRIN1GRIN2A | |
| Hydrochloric Acid SCHEMBL6606586 | 0.79 | ACHE (0.63) | MAPTACHEBCHEGRIN1GRIN2A | |
| SCHEMBL8006170 | 0.79 | ACHE (1.00) | ACHEBCHEGRIN1GRIN2ACHRM1 | |
| Hydrochloric Acid SCHEMBL29817833 | 0.78 | ACHE (1.00) | ACHEBCHEGRIN1GRIN2ACHRM1 | |
| Hydrochloric Acid SCHEMBL29817811 | 0.78 | ACHE (1.00) | ACHEBCHEGRIN1GRIN2ACHRM1 | |
| SCHEMBL11833516 | 0.77 | MAPT (0.56) | MAPTACHEBCHEGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997462-A1 | NOVEL NAPHTHYRIDINE DERIVATIVES OR SALTS THEREOF | Nippon Kayaku Kabushiki Kaisha (JP) | 2000-05-03 | — | — | EP | claimed |
| EP-0997462-B1 | NOVEL NAPHTHYRIDINE DERIVATIVES OR SALTS THEREOF | NIPPON KAYAKU KK (JP) | 2004-12-22 | — | — | EP | disclosed |
| US-6294547-B1 | Naphthyridine deratives or salts thereof | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2001-09-25 | — | — | US | disclosed |
| EP-0997462-A1 | NOVEL NAPHTHYRIDINE DERIVATIVES OR SALTS THEREOF | Nippon Kayaku Kabushiki Kaisha (JP) | 2000-05-03 | — | — | EP | disclosed |