Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | LTB4R | Q15722 | 4/20 | 0.44 |
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.43 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9247195 | 1.00 | MEN1 (0.56) | MEN1MAPTKMT2ALTB4RCYSLTR1 | |
| SCHEMBL9192704 | 1.00 | MEN1 (0.56) | MEN1MAPTKMT2ALTB4RCYSLTR1 | |
| SCHEMBL9189109 | 0.93 | MEN1 (0.50) | MEN1MAPTKMT2ALTB4RCYSLTR1 | |
| SCHEMBL9191448 | 0.88 | MAPT (0.61) | MEN1MAPTKMT2ALTB4RCYSLTR1 | |
| SCHEMBL28276324 | 0.83 | TLR8 (0.60) | MEN1MAPTKMT2ACYSLTR1CYSLTR2 | |
| SCHEMBL16114537 | 0.83 | TLR8 (0.60) | MEN1MAPTKMT2ACYSLTR1CYSLTR2 | |
| SCHEMBL3531400 | 0.83 | MEN1 (0.56) | MEN1MAPTKMT2ACYSLTR1CYSLTR2 | |
| SCHEMBL8067767 | 0.83 | MEN1 (0.59) | MEN1MAPTKMT2ACYSLTR1CYSLTR2 | |
| SCHEMBL30704390 | 0.83 | MEN1 (0.59) | MEN1MAPTKMT2ACYSLTR1CYSLTR2 | |
| SCHEMBL8359311 | 0.81 | LTB4R (0.62) | MEN1MAPTKMT2ALTB4RCYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6787561-B1 | HYPERLIPIDEMIA, ARTERIOSCLEROSIS; ORAL ADMINISTRATION; SUPPRESSING THE FORMING OF MACROPHAGES | FUJI PHOTO FILM CO., LTD. (JP) | 2004-09-07 | — | — | US | disclosed |
| EP-1197493-B1 | BENZIMIDAZOLE COMPOUNDS | FUJI PHOTO FILM CO LTD (JP) | 2004-03-24 | — | — | EP | disclosed |
| EP-1197493-A1 | BENZIMIDAZOLE COMPOUNDS | FUJI PHOTO FILM CO., LTD. (JP) | 2002-04-17 | — | — | EP | disclosed |