Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | PSMD10 | O75832 | 1/20 | 0.39 |
| ▸ | VDR | P11473 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6603226 | 0.99 | GRM2 (0.41) | GRM2CYP24A1ALDH1A1PTGS2KDM4E | |
| SCHEMBL6609131 | 0.99 | GRM2 (0.41) | GRM2CYP24A1ALDH1A1PTGS2KDM4E | |
| SCHEMBL6604282 | 0.99 | GRM2 (0.41) | GRM2CYP24A1ALDH1A1PTGS2KDM4E | |
| SCHEMBL6606551 | 0.99 | GRM2 (0.41) | GRM2CYP24A1ALDH1A1PTGS2KDM4E | |
| SCHEMBL8380811 | 0.93 | CA12 (0.45) | GRM2ALDH1A1PTGS2KDM4ELMNA | |
| SCHEMBL6608554 | 0.83 | ALDH1A1 (0.41) | CYP24A1ALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL890725 | 0.82 | ALDH1A1 (0.50) | CYP24A1ALDH1A1SMN1; SMN2CA12CA1 | |
| SCHEMBL6604078 | 0.81 | ALDH1A1 (0.44) | CYP24A1ALDH1A1PTGS2KDM4ELMNA | |
| SCHEMBL15532701 | 0.80 | CA12 (0.40) | CYP24A1ALDH1A1PTGS2KDM4ECA12 | |
| SCHEMBL4951882 | 0.80 | ALDH1A1 (0.48) | CYP24A1ALDH1A1SMN1; SMN2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6787561-B1 | HYPERLIPIDEMIA, ARTERIOSCLEROSIS; ORAL ADMINISTRATION; SUPPRESSING THE FORMING OF MACROPHAGES | FUJI PHOTO FILM CO., LTD. (JP) | 2004-09-07 | — | — | US | disclosed |
| EP-1197493-B1 | BENZIMIDAZOLE COMPOUNDS | FUJI PHOTO FILM CO LTD (JP) | 2004-03-24 | — | — | EP | disclosed |
| EP-1197493-A1 | BENZIMIDAZOLE COMPOUNDS | FUJI PHOTO FILM CO., LTD. (JP) | 2002-04-17 | — | — | EP | disclosed |