Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 8/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 8/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2905574 | 0.82 | PDE4A (0.42) | FFAR4PDE4APDGFRBPDGFRAPDE4B | |
| SCHEMBL23207662 | 0.79 | GPR6 (0.38) | PDE4APDE4BS1PR1S1PR3 | |
| SCHEMBL30350700 | 0.79 | FFAR4 (0.40) | FFAR4PDE4APDGFRBPDGFRAPDE4B | |
| SCHEMBL2910247 | 0.79 | FFAR4 (0.40) | FFAR4PDE4APDGFRBPDGFRAPDE4B | |
| SCHEMBL26151328 | 0.79 | MCHR1 (0.46) | FFAR4PDE4APDGFRBPDGFRAPDE4B | |
| SCHEMBL16334172 | 0.78 | LRRK2 (0.39) | POLB | |
| SCHEMBL70397 | 0.77 | KDM4E (0.53) | FFAR4PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL24042899 | 0.76 | MCHR1 (0.42) | PDE4APDGFRBPDGFRAPDE4BPDE4C | |
| SCHEMBL10304986 | 0.76 | RAB9A (0.45) | — | |
| SCHEMBL25510507 | 0.75 | LRRK2 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882714-B1 | SUBSTITUTED VINYLPYRIDINE DERIVATIVES AND DRUGS CONTAINING THE SAME | SS PHARMACEUTICAL CO (JP) | 2004-03-03 | — | — | EP | disclosed |
| US-5935977-A | PHOSPHODIESTERASE IV INHIBITORS, TUMOR NECROSIS FACTOR-ALPHA PRODUCTION INHIBITORS; TREATING INFLAMMATORY AND AUTOIMMUNE DISEASES | SS PHARMACEUTICAL CO., LTD. (JP) | 1999-08-10 | — | — | US | disclosed |
| EP-0882714-A1 | SUBSTITUTED VINYLPYRIDINE DERIVATIVES AND DRUGS CONTAINING THE SAME | SS Pharmaceutical Co., Ltd. (JP) | 1998-12-09 | — | — | EP | disclosed |