Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR2 | P21802 | 16/20 | 0.63 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.49 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.49 |
| ▸ | KIT | P10721 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4476013 | 0.83 | FGFR2 (0.80) | FGFR2PDGFRBPDGFRAKITKDR | |
| SCHEMBL5825982 | 0.81 | FGFR2 (0.68) | FGFR2PDGFRBPDGFRAKITKDR | |
| SCHEMBL4473682 | 0.80 | FGFR2 (0.84) | FGFR2PDGFRBPDGFRAKITKDR | |
| SCHEMBL13936619 | 0.80 | FGFR2 (0.82) | FGFR2PDGFRBPDGFRAKITKDR | |
| SCHEMBL4484850 | 0.79 | FGFR2 (1.00) | FGFR2PDGFRBPDGFRAKITKDR | |
| SCHEMBL4473353 | 0.79 | FGFR2 (0.80) | FGFR2PDGFRBPDGFRAKITKDR | |
| SCHEMBL5826095 | 0.77 | FGFR2 (0.74) | FGFR2PDGFRBPDGFRAKITKDR | |
| SCHEMBL8553216 | 0.76 | FGFR2 (0.72) | FGFR2PDGFRBPDGFRAKITKDR | |
| SCHEMBL5826045 | 0.75 | FGFR2 (0.56) | FGFR2PDGFRBPDGFRAKITKDR | |
| SCHEMBL4476016 | 0.75 | FGFR2 (0.77) | FGFR2PDGFRBPDGFRAKITKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1447405-A1 | QUINOLINE OR QUINAZOLINE DERIVATIVES INHIBITING AUTO-PHOSPHORYLATION OF FIBROBLAST GROWTH FACTOR RECEPTORS | KIRIN BEER KABUSHIKI KAISHA (JP) | 2004-08-18 | — | — | EP | disclosed |