Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SCN4A | P35499 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.36 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.36 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.36 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL969625 | 0.79 | ENPP2 (0.39) | TSHRKMT2AMEN1NPC1RAB9A | |
| SCHEMBL29435906 | 0.77 | TSHR (0.46) | TSHRKMT2AMEN1NPC1RAB9A | |
| SCHEMBL717122 | 0.77 | TSHR (0.46) | TSHRKMT2AMEN1NPC1RAB9A | |
| SCHEMBL30366069 | 0.75 | TSHR (0.45) | TSHRKMT2AMEN1NPC1RAB9A | |
| SCHEMBL350128 | 0.75 | TSHR (0.45) | TSHRKMT2AMEN1NPC1RAB9A | |
| SCHEMBL22056735 | 0.75 | TSHR (0.45) | TSHRKMT2AMEN1NPC1RAB9A | |
| Hydrogen Peroxide SCHEMBL28159758 | 0.74 | TSHR (0.48) | TSHRKMT2AMEN1NPC1RAB9A | |
| SCHEMBL22878 | 0.73 | TSHR (0.53) | TSHRKMT2AMEN1NPC1RAB9A | |
| SCHEMBL29349760 | 0.73 | TSHR (0.53) | TSHRKMT2AMEN1NPC1RAB9A | |
| SCHEMBL30197899 | 0.73 | CA1 (0.44) | TSHRKMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1423386-A1 | THIOPHENYLTHIOPYRANE DIOXIDES AS MMP OR TNF-ALPHA INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-06-02 | — | — | EP | disclosed |
| WO-2003022842-A1 | THIOPHENYLTHIOPYRANE DIOXIDES AS MMP OR TNF-ALPHA INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-03-20 | — | — | WO | disclosed |