Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | MPI | P34949 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | CASP6 | P55212 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6602089 | 0.84 | F2 (0.33) | — | |
| SCHEMBL6606294 | 0.82 | ALDH1A1 (0.42) | ALDH1A1KDM4EHTTMAPTMEN1 | |
| SCHEMBL8911834 | 0.78 | ALDH1A1 (0.60) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL6608321 | 0.76 | TLR2 (0.36) | ALDH1A1KDM4EENPP2MAPTMEN1 | |
| SCHEMBL8129450 | 0.72 | GRIA1 (0.47) | ALDH1A1MAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL6604122 | 0.69 | ALDH1A1 (0.42) | ALDH1A1MAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL8903008 | 0.69 | ALDH1A1 (0.53) | ALDH1A1MAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL8143837 | 0.68 | NR2E1 (0.42) | ALDH1A1KDM4EMAPTTDP1MPI | |
| SCHEMBL9807537 | 0.68 | ALDH1A1 (0.51) | ALDH1A1MAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL462851 | 0.66 | ALDH1A1 (0.49) | ALDH1A1MAPTMEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1161344-C | 6,7-asymmetrically disubstituted quinoxalinecarboxylic acid derivatives, addition salts thereof and process for preparation of both | ������ҩ��ʽ���� | 2004-08-11 | — | — | CN | disclosed |
| EP-1020453-B1 | 6,7-ASYMMETRICALLY DISUBSTITUTED QUINOXALINECARBOXYLIC ACID DERIVATIVES, ADDITION SALTS THEREOF, AND PROCESSES FOR THE PREPARATION OF BOTH | KYORIN SEIYAKU KK (JP) | 2004-05-19 | — | — | EP | disclosed |
| US-6348461-B1 | CENTRAL NERVOUS SYSTEM ANTAGONIST WITH HETEROCYCLIC SUBSTITUENTS | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2002-02-19 | — | — | US | disclosed |
| CN-1269794-A | 6,7-asymmetrically disubstituted quinoxalinecarboxylic acid derivatives, addition salts thereof and process for preparation of both | KYORIN SEIYAKU KK (JP) | 2000-10-11 | — | — | CN | disclosed |
| EP-1020453-A1 | 6,7-ASYMMETRICALLY DISUBSTITUTED QUINOXALINECARBOXYLIC ACID DERI VATIVES, ADDITION SALTS THEREOF, AND PROCESSES FOR THE PREPARATION OF BOTH | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2000-07-19 | — | — | EP | disclosed |