SCHEMBL6608345

SCHEMBL6608345

c1ccc2[nH]c(OCCCCCSc3nc4ccccc4[nH]3)nc2c1

nearest known ligand 0.63

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.63
NPC1 O15118 3/20 0.62
RAB9A P51151 2/20 0.62
LMNA P02545 6/20 0.62
KMT2A Q03164 3/20 0.62
MAPT P10636 3/20 0.62
HTT P42858 3/20 0.62
AR P10275 9/20 0.61
SMN1; SMN2 Q16637 3/20 0.61
TP53 P04637 1/20 0.61
ALDH1A1 P00352 2/20 0.58
MEN1 O00255 2/20 0.58
EPHX2 P34913 1/20 0.57
HPGD P15428 1/20 0.56
POLB P06746 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14304387 0.87 BCHE (0.83) BCHENPC1RAB9ALMNAKMT2A
SCHEMBL6141660 0.87 BCHE (0.83) BCHENPC1RAB9ALMNAKMT2A
SCHEMBL14303261 0.87 BCHE (0.83) BCHENPC1RAB9ALMNAKMT2A
SCHEMBL14303260 0.87 BCHE (0.83) BCHENPC1RAB9ALMNAKMT2A
SCHEMBL14304381 0.87 BCHE (0.83) BCHENPC1RAB9ALMNAKMT2A
Bromide SCHEMBL5084026 0.85 BCHE (0.80) BCHENPC1RAB9ALMNAKMT2A
SCHEMBL14304932 0.85 BCHE (0.86) BCHENPC1RAB9ALMNAKMT2A
SCHEMBL6603620 0.83 BCHE (0.58) BCHENPC1RAB9ALMNAKMT2A
SCHEMBL6604484 0.83 BCHE (0.58) BCHENPC1RAB9ALMNAKMT2A
SCHEMBL6603577 0.83 AR (0.68) BCHENPC1RAB9ALMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6787561-B1 HYPERLIPIDEMIA, ARTERIOSCLEROSIS; ORAL ADMINISTRATION; SUPPRESSING THE FORMING OF MACROPHAGES FUJI PHOTO FILM CO., LTD. (JP) 2004-09-07 US disclosed
EP-1197493-B1 BENZIMIDAZOLE COMPOUNDS FUJI PHOTO FILM CO LTD (JP) 2004-03-24 EP disclosed
EP-1197493-A1 BENZIMIDAZOLE COMPOUNDS FUJI PHOTO FILM CO., LTD. (JP) 2002-04-17 EP disclosed