Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP13 | P45452 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 5/20 | 0.33 |
| ▸ | CA12 | O43570 | 4/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | PER2 | O15055 | 1/20 | 0.32 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.32 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.32 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP7 | P09237 | 1/20 | 0.32 |
| ▸ | MMP10 | P09238 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | MMP12 | P39900 | 1/20 | 0.32 |
| ▸ | MMP14 | P50281 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6403067 | 1.00 | CYP2A6 (0.38) | CYP2A6MMP2MMP13CA2CA12 | |
| SCHEMBL6607289 | 0.92 | MMP2 (0.36) | CYP2A6MMP2MMP13TPSAB1MMP1 | |
| SCHEMBL6608267 | 0.89 | CYP2A6 (0.40) | CYP2A6MMP2MMP13CA2CA12 | |
| SCHEMBL6608264 | 0.89 | CYP2A6 (0.40) | CYP2A6MMP2MMP13CA2CA12 | |
| SCHEMBL6399305 | 0.85 | CYP2A6 (0.36) | CYP2A6MMP2MMP13CA2CA12 | |
| SCHEMBL6405755 | 0.82 | HPGD (0.38) | CYP2A6MMP2MMP13CA2CA12 | |
| SCHEMBL6405750 | 0.82 | HPGD (0.38) | CYP2A6MMP2MMP13CA2CA12 | |
| SCHEMBL6399504 | 0.82 | CYP2A6 (0.36) | CYP2A6MMP2MMP13CA2CA12 | |
| SCHEMBL6608049 | 0.82 | CYP2A6 (0.36) | CYP2A6MMP2MMP13CA2CA12 | |
| SCHEMBL6399565 | 0.81 | CYP2A6 (0.35) | CYP2A6MMP2MMP13CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289980-B1 | BICYCLYL OR HETEROBICYCLYLMETHANESULFONYLAMINO-SUBSTITUTED N-HYDROXYFORMAMIDES | SMITHKLINE BEECHAM PLC (GB) | 2004-11-17 | — | — | EP | claimed |