Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 6/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.43 |
| ▸ | PTPN7 | P35236 | 5/20 | 0.42 |
| ▸ | PTPN12 | Q05209 | 5/20 | 0.42 |
| ▸ | PTPN22 | Q9Y2R2 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6608598 | 1.00 | PDE4A (0.43) | PDE4APDE4BPDE4CPDE4DPTPN7 | |
| SCHEMBL6609657 | 0.92 | MAPT (0.41) | PDE4APDE4BPDE4CPDE4DPTPN7 | |
| SCHEMBL6609662 | 0.92 | MAPT (0.41) | PDE4APDE4BPDE4CPDE4DPTPN7 | |
| SCHEMBL6605851 | 0.89 | PDE4A (0.49) | PDE4APDE4BPDE4CPDE4DPTPN7 | |
| SCHEMBL6605848 | 0.89 | PDE4A (0.49) | PDE4APDE4BPDE4CPDE4DPTPN7 | |
| SCHEMBL6607907 | 0.85 | SMN1; SMN2 (0.46) | PDE4BPOLBHPGDL3MBTL1SMN1; SMN2 | |
| SCHEMBL6607901 | 0.85 | SMN1; SMN2 (0.46) | PDE4BPOLBHPGDL3MBTL1SMN1; SMN2 | |
| SCHEMBL6609749 | 0.83 | PDE4A (0.48) | PDE4APDE4BPDE4CPDE4DPTPN7 | |
| SCHEMBL6609752 | 0.83 | PDE4A (0.48) | PDE4APDE4BPDE4CPDE4DPTPN7 | |
| SCHEMBL6607249 | 0.82 | PDE4A (0.40) | PDE4APDE4BPDE4CPDE4DPTPN7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882714-B1 | SUBSTITUTED VINYLPYRIDINE DERIVATIVES AND DRUGS CONTAINING THE SAME | SS PHARMACEUTICAL CO (JP) | 2004-03-03 | — | — | EP | disclosed |
| EP-0882714-A1 | SUBSTITUTED VINYLPYRIDINE DERIVATIVES AND DRUGS CONTAINING THE SAME | SS Pharmaceutical Co., Ltd. (JP) | 1998-12-09 | — | — | EP | disclosed |