Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | IGF2R | P11717 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 2/20 | 0.38 |
| ▸ | NQO1 | P15559 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6607907 | 1.00 | SMN1; SMN2 (0.46) | SMN1; SMN2EGFRRECQLHIF1APDGFRB | |
| SCHEMBL6606448 | 0.90 | EGFR (0.44) | SMN1; SMN2EGFRRECQLHIF1APDGFRB | |
| SCHEMBL6606444 | 0.90 | EGFR (0.44) | SMN1; SMN2EGFRRECQLHIF1APDGFRB | |
| SCHEMBL6608598 | 0.85 | PDE4A (0.43) | SMN1; SMN2EGFRRECQLHIF1APDGFRB | |
| SCHEMBL6608593 | 0.85 | PDE4A (0.43) | SMN1; SMN2EGFRRECQLHIF1APDGFRB | |
| SCHEMBL6609657 | 0.84 | MAPT (0.41) | SMN1; SMN2EGFRRECQLHIF1APDGFRB | |
| SCHEMBL6609662 | 0.84 | MAPT (0.41) | SMN1; SMN2EGFRRECQLHIF1APDGFRB | |
| SCHEMBL6605043 | 0.82 | MAPT (0.43) | SMN1; SMN2EGFRRECQLHIF1APDGFRB | |
| SCHEMBL6605036 | 0.82 | MAPT (0.43) | SMN1; SMN2EGFRRECQLHIF1APDGFRB | |
| SCHEMBL6611008 | 0.81 | SMN1; SMN2 (0.38) | SMN1; SMN2EGFRRECQLHIF1APDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882714-B1 | SUBSTITUTED VINYLPYRIDINE DERIVATIVES AND DRUGS CONTAINING THE SAME | SS PHARMACEUTICAL CO (JP) | 2004-03-03 | — | — | EP | disclosed |
| EP-0882714-A1 | SUBSTITUTED VINYLPYRIDINE DERIVATIVES AND DRUGS CONTAINING THE SAME | SS Pharmaceutical Co., Ltd. (JP) | 1998-12-09 | — | — | EP | disclosed |