Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR1 | P47211 | 8/20 | 0.43 |
| ▸ | GALR2 | O43603 | 7/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.38 |
| ▸ | CCND1 | P24385 | 1/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | INSR | P06213 | 1/20 | 0.36 |
| ▸ | AXL | P30530 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5550316 | 1.00 | GALR1 (0.43) | GALR1GALR2L3MBTL1CYP2D6CYP2C19 | |
| SCHEMBL5553491 | 0.89 | GALR1 (0.46) | GALR1GALR2CDK1CDK4CCNB1 | |
| SCHEMBL4835999 | 0.88 | GALR1 (0.40) | GALR1GALR2CYP2D6CYP2C19CDK1 | |
| SCHEMBL4838559 | 0.88 | GALR1 (0.41) | GALR1GALR2CYP2D6CYP2C19CDK1 | |
| SCHEMBL4829533 | 0.87 | GALR1 (0.41) | GALR1GALR2CYP2D6CYP2C19CDK1 | |
| SCHEMBL5549889 | 0.87 | GALR1 (0.45) | GALR1GALR2L3MBTL1CYP2D6CYP2C19 | |
| SCHEMBL6273065 | 0.85 | GALR1 (0.41) | GALR1GALR2L3MBTL1CYP2D6CYP2C19 | |
| SCHEMBL4832137 | 0.84 | GALR1 (0.47) | GALR1GALR2DRD2 | |
| SCHEMBL6861989 | 0.84 | L3MBTL1 (0.45) | L3MBTL1CYP2D6CYP2C19ALDH1A1SMN1; SMN2 | |
| SCHEMBL6229931 | 0.84 | GALR1 (0.42) | GALR1GALR2L3MBTL1CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1436266-A4 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | REDDY US THERAPEUTICS INC (US) | 2004-12-22 | — | — | EP | claimed |
| EP-1436266-A2 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | Reddy US Therapeutics, Inc. (US) | 2004-07-14 | — | — | EP | claimed |
| WO-2003024926-A2 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | REDDY US THERAPEUTICS, INC. (US) | 2003-03-27 | — | — | WO | claimed |