SCHEMBL6608924

SCHEMBL6608924

FC(F)(F)C[CH]C(F)(F)C(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21225363 0.73
SCHEMBL3342425 0.72
SCHEMBL2483571 0.71
SCHEMBL21647362 0.71
SCHEMBL6059984 0.67
SCHEMBL603660 0.67
SCHEMBL2872491 0.67
SCHEMBL5788268 0.67
SCHEMBL3698104 0.65 TSHR (0.33)
SCHEMBL28161197 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180010015-A1 COMPOSITION FOR FORMING EASY-TO-DETACH THIN RESIN FILM, AND EASY-TO-DETACH THIN RESIN FILM NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-01-11 US disclosed
US-6800651-B2 Potentiators of glutamate receptors ELI LILLY AND COMPANY 2004-10-05 US disclosed
EP-1379248-A1 TRICYCLIC COMPOUNDS USEFUL AS HIV REVERSE TRANSCRIPTASE INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2004-01-14 EP disclosed
US-20040006114-A1 Potentiators of glutamate receptors ELI LILLY AND COMPANY 2004-01-08 US disclosed
WO-2002085365-A1 TRICYCLIC COMPOUNDS USEFUL AS HIV REVERSE TRANSCRIPTASE INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2002-10-31 WO disclosed
US-4769456-A ANTIULCER AGENTS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1988-09-06 US disclosed
EP-0233760-A1 Sulfenamide derivatives and their production Takeda Chemical Industries, Ltd. (JP) 1987-08-26 EP disclosed