⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5468190 | 0.81 | — | — | |
| SCHEMBL10912363 | 0.79 | — | — | |
| SCHEMBL3698104 | 0.78 | TSHR (0.33) | — | |
| SCHEMBL1307768 | 0.77 | LMNA (0.33) | — | |
| SCHEMBL28039217 | 0.77 | LMNA (0.33) | — | |
| SCHEMBL5463398 | 0.77 | LMNA (0.33) | — | |
| SCHEMBL10913022 | 0.77 | LMNA (0.33) | — | |
| SCHEMBL28173111 | 0.77 | LMNA (0.33) | — | |
| SCHEMBL518040 | 0.72 | — | — | |
| SCHEMBL5611825 | 0.71 | TSHR (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9663502-B2 | 2-Acylamidomethyl and sulfonylamidomethyl benzoxazine carbamates for inhibition of RORgamma activity and the treatment of disease | LYCERA CORPORATION (US) | 2017-05-30 | — | — | US | claimed |
| CN-115554294-A | 7-substituted 1-arylnaphthyridine-3-carboxamides and their use | 拜耳股份公司 | 2023-01-03 | — | — | CN | disclosed |
| CN-109689656-B | 7-substituted 1-arylnaphthyridine-3-carboxamides and their use | 拜耳股份公司 | 2022-10-04 | — | — | CN | disclosed |
| CN-107949562-B | Positive allosteric modulators of muscarinic M2 receptors | 拜耳制药股份公司 | 2021-07-23 | — | — | CN | disclosed |
| EP-3512849-B1 | 7-SUBSTITUTED 1-ARYL-NAPHTHYRIDIN-3-CARBOXAMIDES AND THEIR USE | BAYER AG (DE) | 2021-06-23 | — | — | EP | disclosed |
| EP-3782220-A1 | AN ELECTROLYTE COMPOSITION FOR A LITHIUM-ION BATTERY AND A LITHIUM-ION BATTERY | Karlsruher Institut für Technologie (DE) | 2021-02-24 | — | — | EP | disclosed |
| US-10927109-B2 | 7-substituted 1-aryl-naphthyridine-3-carboxylic acid amides and use thereof | BAYER AKTIENGESELLSCHAFT (DE) | 2021-02-23 | — | — | US | disclosed |
| EP-3307741-B1 | POSITIVE ALLOSTERIC MODULATORS OF THE MUSCARIC M2 RECEPTOR | Bayer Pharma AG (DE) | 2020-10-28 | — | — | EP | disclosed |
| EP-3692991-A1 | POSITIVE ALLOSTERIC MODULATORS OF THE MUSCARINIC M2 RECEPTOR | Bayer Pharma Aktiengesellschaft (DE) | 2020-08-12 | — | — | EP | disclosed |
| CN-110352192-A | Heterocyclic compound and harmful arthropod control agent containing same | 住友化学株式会社 | 2019-10-18 | — | — | CN | disclosed |
| US-20120041009-A1 | PYRIMIDINE COMPOUND AND ITS USE IN PEST CONTROL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-02-16 | — | — | US | disclosed |
| EP-2215086-B1 | PYRIDINE COMPOUND, PESTICIDAL COMPOSITION AND METHOD OF CONTROLLING PEST | SUMITOMO CHEMICAL CO (JP) | 2011-08-24 | — | — | EP | disclosed |
| WO-2010134478-A1 | PYRIMIDINE COMPOUND AND ITS USE IN PEST CONTROL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-11-25 | — | — | WO | disclosed |
| US-20100286148-A1 | PYRIDINE COMPOUND, PESTICIDAL COMPOSITION AND METHOD OF CONTROLLING PEST | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-11-11 | — | — | US | disclosed |
| EP-2215086-A1 | PYRIDINE COMPOUND, PESTICIDAL COMPOSITION AND METHOD OF CONTROLLING PEST | Sumitomo Chemical Company, Limited (JP) | 2010-08-11 | — | — | EP | disclosed |
| WO-2009066786-A1 | PYRIDINE COMPOUND, PESTICIDAL COMPOSITION AND METHOD OF CONTROLLING PEST | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-05-28 | — | — | WO | disclosed |
| EP-0114413-B1 | FLUORALKYLOXYALKYL-SUBSTITUENTS CONTAINING POLYDIORGANOPOLYSILOXANES, AND THEIR USE | Wacker-Chemie GmbH (DE) | 1986-11-26 | — | — | EP | disclosed |
| US-4549004-A | ANTIFOAM LUBRICANT | WACKER-CHEMIE GMBH (DE) | 1985-10-22 | — | — | US | disclosed |
| US-4489201-A | Fluoroalkyloxylakyl containing organopolysiloxanes | WACKER-CHEMIE GMBH (DE) | 1984-12-18 | — | — | US | disclosed |
| EP-0114413-A1 | Fluoralkyloxyalkyl-substituents containing polydiorganopolysiloxanes, and their use | Wacker-Chemie GmbH (DE) | 1984-08-01 | — | — | EP | disclosed |