⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL163547 | 1.00 | — | — | |
| SCHEMBL28453824 | 0.79 | — | — | |
| SCHEMBL514591 | 0.67 | — | — | |
| SCHEMBL162543 | 0.67 | — | — | |
| SCHEMBL229109 | 0.67 | — | — | |
| SCHEMBL460995 | 0.67 | — | — | |
| SCHEMBL166077 | 0.67 | — | — | |
| SCHEMBL8855976 | 0.67 | — | — | |
| SCHEMBL1760689 | 0.67 | — | — | |
| SCHEMBL1002858 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6815449-B2 | AN IMMUNOSUPPRESSANTS FOR TREATING AUTOIMMUNE DISEASES, ANTIALLERGIC AGENTS, ANTITUMOR AGENTS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2004-11-09 | — | — | US | claimed |
| EP-1097934-B1 | LK6-A DERIVATIVES | KYOWA HAKKO KOGYO KK (JP) | 2004-10-13 | — | — | EP | claimed |
| US-20030181722-A1 | LK6-A derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2003-09-25 | — | — | US | claimed |
| US-6613774-B1 | Alkaloids used as immunosuppressants, antiproliferative or antitumor agents for therapy of autoimmune diseases or allergies | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2003-09-02 | — | — | US | claimed |
| EP-1097934-A1 | LK6-A DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2001-05-09 | — | — | EP | claimed |
| US-5734060-A | Method of preparing acylisocyanates | SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) | 1998-03-31 | — | — | US | claimed |
| US-6815449-B2 | AN IMMUNOSUPPRESSANTS FOR TREATING AUTOIMMUNE DISEASES, ANTIALLERGIC AGENTS, ANTITUMOR AGENTS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2004-11-09 | — | — | US | disclosed |
| EP-1097934-B1 | LK6-A DERIVATIVES | KYOWA HAKKO KOGYO KK (JP) | 2004-10-13 | — | — | EP | disclosed |
| EP-1097934-B1 | LK6-A DERIVATIVES | KYOWA HAKKO KOGYO KK (JP) | 2004-10-13 | — | — | EP | disclosed |
| US-20030181722-A1 | LK6-A derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2003-09-25 | — | — | US | disclosed |
| US-6613774-B1 | Alkaloids used as immunosuppressants, antiproliferative or antitumor agents for therapy of autoimmune diseases or allergies | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2003-09-02 | — | — | US | disclosed |
| EP-1097934-A4 | LK6-A DERIVATIVES | KYOWA HAKKO KOGYO KK (JP) | 2001-10-04 | — | — | EP | disclosed |
| EP-1097934-A1 | LK6-A DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2001-05-09 | — | — | EP | disclosed |
| EP-1097934-A1 | LK6-A DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2001-05-09 | — | — | EP | disclosed |
| EP-0767166-B1 | Process for the preparation of acyl isocyanates | SOC NAT (FR) | 2000-05-31 | — | — | EP | disclosed |
| WO-2000002879-A1 | LK6-A DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2000-01-20 | — | — | WO | disclosed |
| US-5734060-A | Method of preparing acylisocyanates | SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) | 1998-03-31 | — | — | US | disclosed |
| EP-0767166-A1 | Process for the preparation of acyl isocyanates | SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) | 1997-04-09 | — | — | EP | disclosed |
| US-4055634-A | ALUMINUM ALKOXIDE | HOFFMANN-LA ROCHE, INC. (US) | 1977-10-25 | — | — | US | disclosed |