Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 4/20 | 0.66 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | OXTR | P30559 | 1/20 | 0.40 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6609187 | 0.95 | GSK3B (0.68) | GSK3BCES2CES1DAORXFP1 | |
| SCHEMBL2070109 | 0.87 | GSK3B (0.72) | GSK3BCES2CES1DAORXFP1 | |
| SCHEMBL15988673 | 0.83 | GSK3B (0.73) | GSK3BCES2CES1DAORXFP1 | |
| SCHEMBL28382588 | 0.83 | GSK3B (0.58) | GSK3BCES2CES1DAORXFP1 | |
| SCHEMBL1165071 | 0.81 | GSK3B (0.56) | GSK3BCES2CES1DAORXFP1 | |
| SCHEMBL2009655 | 0.81 | GSK3B (0.56) | GSK3BCES2CES1DAORXFP1 | |
| SCHEMBL9425448 | 0.81 | GSK3B (0.65) | GSK3BDAOGAAKDM4EKMT2A | |
| SCHEMBL12541939 | 0.81 | GSK3B (0.59) | GSK3BCES2CES1DAORXFP1 | |
| SCHEMBL3998532 | 0.80 | GSK3B (1.00) | GSK3BCES2CES1DAORXFP1 | |
| SCHEMBL6209758 | 0.78 | GSK3B (0.56) | GSK3BCES2CES1DAORXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140895-B1 | THIOPYRAN COMPOUNDS AS INHIBITORS OF MMP | FUJISAWA PHARMACEUTICAL CO (JP) | 2004-03-24 | — | — | EP | disclosed |
| CN-1343206-A | Cyclocompound | FUJISAWA PHARMACEUTICAL CO (JP) | 2002-04-03 | — | — | CN | disclosed |