Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.66 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.66 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.34 |
| ▸ | CDK2 | P24941 | 4/20 | 0.34 |
| ▸ | CDK1 | P06493 | 3/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | TK1 | P04183 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 6-Deoxy Penciclovir SCHEMBL29797811 | 1.00 | ALDH1A1 (0.66) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 | |
| 6-Deoxy Penciclovir SCHEMBL3324010 | 0.99 | ALDH1A1 (0.65) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 | |
| SCHEMBL10711562 | 0.93 | KDM4E (0.62) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 | |
| 6-Deoxy Penciclovir SCHEMBL4207112 | 0.92 | KDM4E (0.71) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 | |
| SCHEMBL9763803 | 0.87 | KDM4E (0.58) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 | |
| SCHEMBL9763808 | 0.87 | KDM4E (0.58) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 | |
| SCHEMBL19242423 | 0.86 | KDM4E (0.60) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 | |
| Detiviciclovir SCHEMBL7744996 | 0.85 | KDM4E (0.52) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 | |
| SCHEMBL1875480 | 0.85 | KDM4E (0.62) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 | |
| Monoacetyl-6-Deoxy Penciclovir SCHEMBL1878763 | 0.85 | KDM4E (0.89) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 197 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9549930-B2 | Combined systemic and topical treatment of disordered and/or prodromal stage tissue | QUADEX PHARMACEUTICALS, LLC (US) | 2017-01-24 | — | — | US | claimed |
| US-9545408-B2 | Combined systemic and topical treatment of disordered tissues | QUADEX PHARMACEUTICALS, INC. (US) | 2017-01-17 | — | — | US | claimed |
| US-7148349-B2 | Cyclic phosphate diesters of 1,3-propane-1-aryl diols and their use in preparing prodrugs | METABASIS THERAPEUTICS, INC. (US) | 2006-12-12 | — | — | US | claimed |
| US-5250688-A | Treating herpes virus infections | BEECHAM GROUP P.L.C. (GB) | 1993-10-05 | — | — | US | claimed |
| EP-0182024-B1 | PURINE DERIVATIVES AND THEIR PHARMACEUTICAL USE | BEECHAM GROUP PLC (GB) | 1991-04-03 | — | — | EP | claimed |
| EP-0186640-B1 | DERIVATIVES OF PURINE, PROCESS FOR THEIR PREPARATION AND A PHARMACEUTICAL PREPARATION | Medivir Aktiebolag (SE) | 1990-02-07 | — | — | EP | claimed |
| WO-1987005604-A1 | 2-AMINOPURINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | BEECHAM GROUP P.L.C. (GB) | 1987-09-24 | — | — | WO | claimed |
| EP-0186640-A1 | Derivatives of purine, process for their preparation and a pharmaceutical preparation | Medivir Aktiebolag (SE) | 1986-07-02 | — | — | EP | claimed |
| EP-0182024-A2 | Purine derivatives and their pharmaceutical use | BEECHAM GROUP PLC (GB) | 1986-05-28 | — | — | EP | claimed |
| JP-6025241-A | — | — | None | — | — | JP | disclosed |
| CN-112979653-A | Method for synthesizing famciclovir by using microchannel reactor | 上药康丽（常州）药业有限公司 | 2021-06-18 | — | — | CN | disclosed |
| EP-3692015-A1 | NOVEL GLUTAMINE ANTAGONISTS AND USES THEREOF | The John Hopkins University (US) | 2020-08-12 | — | — | EP | disclosed |
| WO-2019071110-A1 | NOVEL GLUTAMINE ANTAGONISTS AND USES THEREOF | THE JOHN HOPKINS UNIVERSITY (US) | 2019-04-11 | — | — | WO | disclosed |
| US-10080785-B2 | Albumin fusion proteins | NOVOZYMES BIOPHARMA DK A/S (DK) | 2018-09-25 | — | — | US | disclosed |
| US-5036071-A | Herper virus | MEDIVIR AB (SE) | 1991-07-30 | — | — | US | disclosed |
| EP-0182024-B1 | PURINE DERIVATIVES AND THEIR PHARMACEUTICAL USE | BEECHAM GROUP PLC (GB) | 1991-04-03 | — | — | EP | disclosed |
| EP-0186640-B1 | DERIVATIVES OF PURINE, PROCESS FOR THEIR PREPARATION AND A PHARMACEUTICAL PREPARATION | Medivir Aktiebolag (SE) | 1990-02-07 | — | — | EP | disclosed |
| EP-0302644-A2 | Purine compounds and their preparation | BEECHAM GROUP PLC (GB) | 1989-02-08 | — | — | EP | disclosed |
| WO-1987005604-A1 | 2-AMINOPURINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | BEECHAM GROUP P.L.C. (GB) | 1987-09-24 | — | — | WO | disclosed |
| EP-0182024-A2 | Purine derivatives and their pharmaceutical use | BEECHAM GROUP PLC (GB) | 1986-05-28 | — | — | EP | disclosed |