SCHEMBL660977

SCHEMBL660977

Cc1ccc([N+](=O)[O-])o1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15200988 0.82 LMNA (0.58)
SCHEMBL15617561 0.76 KMT2A (0.45)
SCHEMBL17975318 0.75 KMT2A (0.66)
SCHEMBL2714851 0.73 KDM1A (0.47)
SCHEMBL10028335 0.73 LMNA (0.46)
SCHEMBL11391278 0.71
SCHEMBL660976 0.71
SCHEMBL8587843 0.71
SCHEMBL11752214 0.71
SCHEMBL5948310 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 263 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090018148-A1 Xanthine Derivatives, Processes For Preparing Them And Their Uses UCB PHARMA, S.A. (BE) 2009-01-15 US claimed
EP-1963325-A2 XANTHINE DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES UCB Pharma, S.A. (BE) 2008-09-03 EP claimed
WO-2007065595-A2 XANTHINE DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES UCB PHARMA, S.A. (BE) 2007-06-14 WO claimed
EP-1206589-B1 ACCELERATOR FOR PHOSPHATING METAL SURFACES HENKEL KGAA (DE) 2003-04-16 EP claimed
US-6166074-A Pharmaceutical compositions NORSK HYDRO A.S. (NO) 2000-12-26 US claimed
CN-116637634-B Preparation and application of furanmethanol compound hydrogenolysis catalyst 南昌大学 2025-06-13 CN disclosed
US-20230277501-A1 METHODS AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION THE JOHNS HOPKINS UNIVERSITY 2023-09-07 US disclosed
CN-116637634-A Preparation and application of furanmethanol compound hydrogenolysis catalyst 南昌大学 2023-08-25 CN disclosed
US-20230033195-A1 METHODS AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION THE JOHNS HOPKINS UNIVERSITY 2023-02-02 US disclosed
US-20220218665-A1 METHODS AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION UNIV JOHNS HOPKINS (US) 2022-07-14 US disclosed
US-11160785-B2 Methods and compositions for improving cognitive function AGENEBIO INC. (US) 2021-11-02 US disclosed
US-20210244709-A1 METHODS AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION THE JOHNS HOPKINS UNIVERSITY 2021-08-12 US disclosed
WO-1994025471-A1 PHOSPHORAMIDATES USEFUL AS ANTITUMOR AGENTS RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1994-11-10 WO disclosed
US-4389477-A Photoconductive composition sensitized by a thiobarbituric acid derivative FUJI PHOTO FILM CO., LTD. (JP) 1983-06-21 US disclosed
US-4136189-A 2-(5-NITRO-FURFURYLIDENE)-AMINO-BENZIMIDOLES AND FUNGICIDAL COMPOSITIONS CONTAINING THE SAME CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA R.T. (HU) 1979-01-23 US disclosed
US-4072496-A 2,6-Dichlorobenzaldehyde tetrahydro-2-furoyl hydrazone and its use as a ripener for sugarcane W. R. GRACE & CO. (US) 1978-02-07 US disclosed
US-3992186-A INCREASING SUCROSE YIELD HAWAIIAN SUGAR PLANTERS' ASSOCIATION (US) 1976-11-16 US disclosed
US-3974277-A PESTICIDES DIAMOND SHAMROCK CORPORATION (US) 1976-08-10 US disclosed
US-3973021-A 2-[2-(5-Nitro-2-furyl)vinyl]-4-(phydroxyanilino)quinazoline as a bactericide DIAMOND SHAMROCK CORPORATION (US) 1976-08-03 US disclosed
US-3970648-A PESTICIDE, ANIMAL GROWTH REGULATOR DIAMOND SHAMROCK CORPORATION (US) 1976-07-20 US disclosed