Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 8/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 2/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8050515 | 0.98 | DNM1 (0.53) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL12096349 | 0.98 | DNM1 (0.53) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL19809920 | 0.98 | DNM1 (0.53) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL8052574 | 0.98 | DNM1 (0.53) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL10994150 | 0.98 | DNM1 (0.53) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL8048713 | 0.98 | DNM1 (0.53) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL9013817 | 0.98 | DNM1 (0.53) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL3492554 | 0.93 | DNM1 (0.42) | DNM1OPRM1MEN1KMT2AALDH1A1 | |
| Acetic Acid SCHEMBL11767732 | 0.88 | DNM1 (0.44) | DNM1TSHRTLR2DPP7 | |
| SCHEMBL7720705 | 0.86 | DNM1 (0.50) | DNM1MEN1KMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1389202-B1 | 2,6-SUBSTITUTED CHROMAN DERIVATIVES USEFUL AS BETA-3 ADRENORECEPTOR AGONISTS | BAYER PHARMACEUTICALS CORP (US) | 2004-09-29 | — | — | EP | disclosed |
| US-4140779-A | ANTIDEPRESSANTS | AYERST, MCKENNA AND HARRISON LIMITED (CA) | 1979-02-20 | — | — | US | disclosed |
| US-4140779-A | ANTIDEPRESSANTS | AYERST, MCKENNA AND HARRISON LIMITED (CA) | 1979-02-20 | — | — | US | disclosed |