Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6610318 | 1.00 | SRD5A2 (0.37) | SRD5A2MAPTKMT2AALDH1A1HPGD | |
| SCHEMBL6609903 | 0.88 | MMP1 (0.39) | MAPTKMT2AALDH1A1HPGDMAOB | |
| SCHEMBL6609901 | 0.88 | MMP1 (0.39) | MAPTKMT2AALDH1A1HPGDMAOB | |
| SCHEMBL6616648 | 0.88 | MAOB (0.39) | SRD5A2MAPTKMT2AALDH1A1HPGD | |
| SCHEMBL6616653 | 0.88 | MAOB (0.39) | SRD5A2MAPTKMT2AALDH1A1HPGD | |
| Iodide SCHEMBL6612377 | 0.81 | PLG (0.37) | SRD5A2MAPTKMT2AALDH1A1HPGD | |
| Iodide SCHEMBL6612373 | 0.81 | PLG (0.37) | SRD5A2MAPTKMT2AALDH1A1HPGD | |
| SCHEMBL6611593 | 0.79 | HDAC1 (0.39) | MAPTKMT2AALDH1A1HPGDMAOB | |
| SCHEMBL6611592 | 0.79 | HDAC1 (0.39) | MAPTKMT2AALDH1A1HPGDMAOB | |
| SCHEMBL6609674 | 0.78 | MAOB (0.40) | MAPTALDH1A1MAOBLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140895-B1 | THIOPYRAN COMPOUNDS AS INHIBITORS OF MMP | FUJISAWA PHARMACEUTICAL CO (JP) | 2004-03-24 | — | — | EP | disclosed |