Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | OGA | O60502 | 11/20 | 0.38 |
| ▸ | GSK3B | P49841 | 4/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | CLK2 | P49760 | 1/20 | 0.35 |
| ▸ | CLK3 | P49761 | 1/20 | 0.35 |
| ▸ | FLT4 | P35916 | 1/20 | 0.33 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25242583 | 0.87 | FFAR1 (0.43) | FFAR1 | |
| SCHEMBL1987497 | 0.86 | FFAR1 (0.49) | FFAR1 | |
| SCHEMBL657486 | 0.85 | FFAR1 (0.44) | FFAR1GSK3BDYRK1AMETCLK2 | |
| SCHEMBL9100609 | 0.84 | FFAR1 (0.43) | FFAR1OGAGSK3BDYRK1A | |
| SCHEMBL28649940 | 0.84 | FFAR1 (0.46) | FFAR1OGA | |
| SCHEMBL2517121 | 0.84 | FFAR1 (0.47) | FFAR1 | |
| SCHEMBL2572488 | 0.84 | FFAR1 (0.47) | FFAR1CLK2 | |
| SCHEMBL2749177 | 0.82 | FFAR1 (0.46) | FFAR1 | |
| SCHEMBL17801242 | 0.82 | FFAR1 (0.46) | FFAR1 | |
| SCHEMBL21808282 | 0.82 | FFAR1 (0.40) | FFAR1OGADYRK1ACLK2CLK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025124429-A1 | AROMATIC AMINE COMPOUND, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | 北京康辰药业股份有限公司 | 2025-06-19 | — | — | WO | disclosed |
| EP-3956330-A1 | SUBSTITUTED 2-AMINO-PYRAZOLYL-[1,2,4]TRIAZOLO[1,5A] PYRIDINE DERIVATIVES AND USE THEREOF | The Johns Hopkins University (US) | 2022-02-23 | — | — | EP | disclosed |
| US-20220041614-A1 | FUSED TETRACYCLIC COMPOUNDS AND USES THEREOF IN MEDICINE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2022-02-10 | — | — | US | disclosed |
| CN-108368083-B | Heteroaryl compounds and their use as therapeutic agents | 东亚首希控股股份有限公司 | 2022-02-01 | — | — | CN | disclosed |
| WO-2020215094-A1 | SUBSTITUTED 2-AMINO-PYRAZOLYL-[1,2,4]TRIAZOLO[1,5A] PYRIDINE DERIVATIVES AND USE THEREOF | THE JOHNS HOPKINS UNIVERSITY (US) | 2020-10-22 | — | — | WO | disclosed |
| WO-2020215094-A1 | SUBSTITUTED 2-AMINO-PYRAZOLYL-[1,2,4]TRIAZOLO[1,5A] PYRIDINE DERIVATIVES AND USE THEREOF | THE JOHNS HOPKINS UNIVERSITY (US) | 2020-10-22 | — | — | WO | disclosed |
| CN-110964023-A | Fused tetracyclic compounds and application thereof in medicines | 广东东阳光药业有限公司 | 2020-04-07 | — | — | CN | disclosed |
| WO-2020063870-A1 | FUSED TETRACYCLIC COMPOUNDS AND USES THEREOF IN MEDICINE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2020-04-02 | — | — | WO | disclosed |
| US-8378104-B2 | 7-aminofuropyridine derivatives | OSI Pharmaceuticals, LLC (US) | 2013-02-19 | — | — | US | disclosed |
| US-20120046267-A1 | 7-AMINOFUROPYRIDINE DERIVATIVES | OSI PHARMACEUTICALS, INC. | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220041614-A1 | FUSED TETRACYCLIC COMPOUNDS AND USES THEREOF IN MEDICINE | SLC10A1, CYP4A11, CYP11B2 | FFAR1 886/4885OGA 2743/4885GSK3B 651/4885 |
| US-20120046267-A1 | 7-AMINOFUROPYRIDINE DERIVATIVES | MAP3K5, STK17A, MAPKAPK5 | FFAR1 2193/4885OGA 2202/4885GSK3B 393/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.