Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 8/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diphenylacetylene SCHEMBL960609 | 0.69 | APP (1.00) | GRM5APPMAPTKDM4EALDH1A1 | |
| Diphenylacetylene SCHEMBL29188592 | 0.69 | APP (1.00) | GRM5APPMAPTKDM4EALDH1A1 | |
| Diphenylacetylene SCHEMBL68254 | 0.69 | APP (1.00) | GRM5APPMAPTKDM4EALDH1A1 | |
| SCHEMBL4170184 | 0.68 | APP (0.55) | GRM5APPMAPTKDM4EALDH1A1 | |
| SCHEMBL4860070 | 0.67 | GRM5 (1.00) | GRM5APPMAPT | |
| Diphenylacetylene SCHEMBL23754282 | 0.67 | APP (0.92) | GRM5APPMAPTKDM4EALDH1A1 | |
| Diphenylacetylene SCHEMBL31243352 | 0.67 | APP (0.92) | GRM5APPMAPTKDM4EALDH1A1 | |
| Diphenylacetylene SCHEMBL9273707 | 0.67 | APP (0.92) | GRM5APPMAPTKDM4EALDH1A1 | |
| Diphenylacetylene SCHEMBL31286315 | 0.67 | APP (0.92) | GRM5APPMAPTKDM4EALDH1A1 | |
| Diphenylacetylene SCHEMBL28768551 | 0.67 | APP (0.92) | GRM5APPMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1423386-A1 | THIOPHENYLTHIOPYRANE DIOXIDES AS MMP OR TNF-ALPHA INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-06-02 | — | — | EP | disclosed |
| WO-2003022842-A1 | THIOPHENYLTHIOPYRANE DIOXIDES AS MMP OR TNF-ALPHA INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-03-20 | — | — | WO | disclosed |