Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6612378 | 1.00 | SMN1; SMN2 (0.40) | SMN1; SMN2MAPTALDH1A1LMNATDP1 | |
| SCHEMBL6609674 | 0.90 | MAOB (0.40) | SMN1; SMN2MAPTALDH1A1LMNAPOLB | |
| SCHEMBL6609669 | 0.90 | MAOB (0.40) | SMN1; SMN2MAPTALDH1A1LMNAPOLB | |
| SCHEMBL6610527 | 0.90 | SMN1; SMN2 (0.41) | SMN1; SMN2MAPTALDH1A1RAB9APOLB | |
| SCHEMBL6610529 | 0.90 | SMN1; SMN2 (0.41) | SMN1; SMN2MAPTALDH1A1RAB9APOLB | |
| SCHEMBL6610157 | 0.89 | MAPT (0.38) | SMN1; SMN2MAPTALDH1A1LMNAHRH2 | |
| SCHEMBL6610154 | 0.89 | MAPT (0.38) | SMN1; SMN2MAPTALDH1A1LMNAHRH2 | |
| SCHEMBL6611592 | 0.89 | HDAC1 (0.39) | SMN1; SMN2MAPTALDH1A1LMNATDP1 | |
| SCHEMBL6611593 | 0.89 | HDAC1 (0.39) | SMN1; SMN2MAPTALDH1A1LMNATDP1 | |
| SCHEMBL6614722 | 0.82 | IKBKB (0.43) | SMN1; SMN2MAPTALDH1A1LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140895-B1 | THIOPYRAN COMPOUNDS AS INHIBITORS OF MMP | FUJISAWA PHARMACEUTICAL CO (JP) | 2004-03-24 | — | — | EP | disclosed |