Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LOX | P28300 | 1/20 | 0.32 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2537711 | 1.00 | TSHR (0.41) | TSHRALDH1A1TDP1MAPTLTB4R | |
| SCHEMBL6613066 | 1.00 | TSHR (0.41) | TSHRALDH1A1TDP1MAPTLTB4R | |
| SCHEMBL16926969 | 1.00 | TSHR (0.41) | TSHRALDH1A1TDP1MAPTLTB4R | |
| SCHEMBL28914857 | 0.97 | TSHR (0.39) | TSHRALDH1A1TDP1MAPTLTB4R | |
| SCHEMBL1460543 | 0.97 | TSHR (0.43) | TSHRALDH1A1TDP1MAPTLTB4R | |
| SCHEMBL21855179 | 0.95 | TSHR (0.38) | TSHRALDH1A1TDP1MAPTLTB4R | |
| SCHEMBL25775758 | 0.95 | TSHR (0.38) | TSHRALDH1A1TDP1MAPTLTB4R | |
| SCHEMBL15412544 | 0.94 | TSHR (0.41) | TSHRALDH1A1TDP1MAPTLTB4R | |
| SCHEMBL15015838 | 0.88 | ALDH1A1 (0.39) | TSHRALDH1A1TDP1MAPTMEN1 | |
| SCHEMBL25030602 | 0.88 | GAA (0.41) | TSHRALDH1A1TDP1MAPTLTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1215196-B1 | Selective reductive amination of nitriles | AIR PROD & CHEM (US) | 2004-05-12 | — | — | EP | claimed |