SCHEMBL6613809

SCHEMBL6613809

CNc1ccc(-c2ccc(N3C[C@H](CNC(C)=O)OC3=O)cc2F)cn1

nearest known ligand 0.70

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MAOA P21397 7/20 0.64
CALML3 P27482 4/20 0.58
MAOB P27338 3/20 0.58
PTGS1 P23219 2/20 0.58
SDHA P31040 2/20 0.58
LMNA P02545 1/20 0.58
CYP3A4 P08684 1/20 0.53
CYP2C19 P33261 1/20 0.53
F10 P00742 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6791790 0.93 MAOA (0.64) MAOACALML3MAOBPTGS1SDHA
SCHEMBL6796433 0.90 MAOA (0.61) MAOACALML3MAOBPTGS1SDHA
SCHEMBL6612431 0.90 MAOA (0.61) MAOACALML3MAOBPTGS1SDHA
SCHEMBL6797685 0.89 MAOA (0.66) MAOACALML3MAOBPTGS1SDHA
SCHEMBL6614774 0.89 MAOA (0.66) MAOACALML3MAOBPTGS1SDHA
Hydrochloric Acid SCHEMBL6799488 0.89 MAOA (0.60) MAOACALML3MAOBPTGS1SDHA
SCHEMBL6613234 0.89 MAOA (0.60) MAOACALML3MAOBPTGS1SDHA
SCHEMBL6793234 0.89 MAOA (0.63) MAOACALML3MAOBPTGS1SDHA
SCHEMBL3093375 0.88 MAOA (0.65) MAOACALML3MAOBPTGS1SDHA
SCHEMBL14763502 0.88 MAOA (0.65) MAOACALML3MAOBPTGS1SDHA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1289984-A4 NOVEL OXAZOLIDINONE DERIVATIVES AND A PROCESS FOR THE PREPARATION THEREOF DONG A PHARM CO LTD (KR) 2004-11-24 EP disclosed
US-6689779-B2 PYRIDINE OR PYRIMIDINE SUBSTITUTED; ANTIBACTERIAL ACTIVITY; LOW TOXICITY DONG A PHARM. CO., LTD. (KR) 2004-02-10 US disclosed
EP-1289984-A1 NOVEL OXAZOLIDINONE DERIVATIVES AND A PROCESS FOR THE PREPARATION THEREOF Dong A Pharmaceutical Co. Ltd. (KR) 2003-03-12 EP disclosed
WO-2001094342-A1 NOVEL OXAZOLIDINONE DERIVATIVES AND A PROCESS FOR THE PREPARATION THEREOF DONG A PHARM. CO., LTD. (KR) 2001-12-13 WO disclosed