Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | ALPL | P05186 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | HPGDS | O60760 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1007015 | 0.98 | MAPK1 (0.61) | MAPK1ALPLMAPTRAB9AKMT2A | |
| SCHEMBL1312019 | 0.88 | MAPK1 (0.53) | MAPK1ALPLMAPTRAB9AKMT2A | |
| SCHEMBL31136151 | 0.88 | MAPK1 (0.53) | MAPK1ALPLMAPTRAB9AKMT2A | |
| SCHEMBL12092824 | 0.88 | ALPL (0.54) | MAPK1ALPLMAPTRAB9AKMT2A | |
| SCHEMBL25181903 | 0.85 | MAPK1 (0.57) | MAPK1ALPLMAPTRAB9AKMT2A | |
| SCHEMBL13734047 | 0.85 | ALPL (0.58) | MAPK1ALPLMAPTRAB9AKMT2A | |
| SCHEMBL9124815 | 0.84 | MAPK1 (0.49) | MAPK1ALPLMAPTRAB9AKMT2A | |
| SCHEMBL19531952 | 0.83 | ALPL (0.49) | MAPK1ALPLMAPTRAB9AKMT2A | |
| SCHEMBL970232 | 0.82 | ALPL (0.57) | MAPK1ALPLMAPTRAB9AKMT2A | |
| SCHEMBL1665229 | 0.82 | DAO (0.58) | MAPK1ALPLMAPTKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1479678-A1 | Pyrazole-derivatives as factor xa inhibitors | Aventis Pharma Deutschland GmbH (DE) | 2004-11-24 | — | — | EP | disclosed |
| EP-1433788-A1 | Pyrazole-derivatives as factor Xa inhibitors | Aventis Pharma Deutschland GmbH (DE) | 2004-06-30 | — | — | EP | disclosed |