Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.43 |
| ▸ | ESRRG | P62508 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.34 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6614722 | 1.00 | IKBKB (0.43) | IKBKBESRRGESR1MAPTTRPM8 | |
| SCHEMBL6612447 | 0.90 | KDM4E (0.43) | ESRRGMAPTTRPM8HSD17B1HSD17B2 | |
| SCHEMBL6612448 | 0.90 | KDM4E (0.43) | ESRRGMAPTTRPM8HSD17B1HSD17B2 | |
| SCHEMBL6612378 | 0.82 | SMN1; SMN2 (0.40) | MAPTPRKCZALDH1A1LMNAHRH2 | |
| SCHEMBL6612381 | 0.82 | SMN1; SMN2 (0.40) | MAPTPRKCZALDH1A1LMNAHRH2 | |
| SCHEMBL27550027 | 0.81 | IKBKB (0.47) | IKBKBESRRGESR1MAPTHDAC1 | |
| SCHEMBL6613712 | 0.81 | GSK3B (0.41) | ESR1MAPTALDH1A1LMNA | |
| SCHEMBL6613707 | 0.81 | GSK3B (0.41) | ESR1MAPTALDH1A1LMNA | |
| SCHEMBL6610835 | 0.80 | KDM4E (0.43) | ESRRGMAPTTRPM8HSD17B1HSD17B2 | |
| SCHEMBL6610831 | 0.80 | KDM4E (0.43) | ESRRGMAPTTRPM8HSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140895-B1 | THIOPYRAN COMPOUNDS AS INHIBITORS OF MMP | FUJISAWA PHARMACEUTICAL CO (JP) | 2004-03-24 | — | — | EP | disclosed |
| EP-1140895-A2 | THIOPYRAN COMPOUNDS AS INHIBITORS OF MMP | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000040576-A2 | THIOPYRAN COMPOUNDS AS INHIBITORS OF MMP | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-07-13 | — | — | WO | disclosed |