Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 15/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1345807 | 1.00 | CNR2 (0.40) | CNR2CNR1OPRM1OPRK1MAOA | |
| SCHEMBL1493746 | 0.85 | CNR2 (0.42) | CNR2CNR1OPRM1OPRK1RORC | |
| SCHEMBL1493865 | 0.85 | CNR2 (0.42) | CNR2CNR1OPRM1OPRK1RORC | |
| SCHEMBL2845977 | 0.79 | CNR2 (0.41) | CNR2CNR1OPRM1OPRK1MAOA | |
| SCHEMBL28038908 | 0.79 | CNR2 (0.41) | CNR2CNR1OPRM1OPRK1MAOA | |
| SCHEMBL15129890 | 0.79 | CNR2 (0.41) | CNR2CNR1OPRM1OPRK1MAOA | |
| SCHEMBL25494519 | 0.75 | OPRM1 (0.42) | CNR2CNR1OPRM1OPRK1 | |
| SCHEMBL1347339 | 0.72 | DPP4 (0.53) | — | |
| SCHEMBL15130403 | 0.71 | HDAC8 (0.46) | CNR2MAOAMAOB | |
| SCHEMBL29162891 | 0.71 | CNR2 (0.37) | CNR2CNR1OPRM1OPRK1RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1487807-A2 | NEW COMPOUNDS | Sanofi-Aventis (FR) | 2004-12-22 | — | — | EP | disclosed |
| WO-2003074500-A2 | N-AMINOACETYL-PYRROLIDINE-2-CARBONITRILES AND THEIR USE AS DDP-IV INHIBITORS | SANOFI-AVENTIS (FR) | 2003-09-12 | — | — | WO | disclosed |