Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5368821 | 0.76 | GAA (0.41) | GAAMAPT | |
| SCHEMBL11389449 | 0.76 | GAA (0.38) | GAAMAPT | |
| SCHEMBL10964499 | 0.73 | LMNA (0.49) | GAAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL9527218 | 0.72 | GAA (0.38) | GAAMAPT | |
| SCHEMBL9789197 | 0.72 | GAA (0.38) | GAAMAPTNPC1 | |
| SCHEMBL28761886 | 0.72 | GAA (0.38) | GAAMAPT | |
| SCHEMBL11520476 | 0.72 | GAA (0.38) | GAAMAPT | |
| SCHEMBL29254528 | 0.72 | MAPT (0.38) | GAAMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL29141757 | 0.71 | GAA (0.36) | GAAMAPTSMN1; SMN2 | |
| SCHEMBL4703515 | 0.71 | MAPT (0.36) | GAAMAPTALDH1A1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106062092-A | Antifouling composition | 佐敦集团 | 2016-10-26 | — | — | CN | disclosed |
| EP-1481975-A1 | Inhibitors of farnesyl protein transferase | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-12-01 | — | — | EP | disclosed |
| EP-0892797-A4 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | BRISTOL MYERS SQUIBB CO (US) | 2004-10-20 | — | — | EP | disclosed |
| US-6455523-B1 | ADMINISTERING 1,4-BENZODIAZEPINE DERIVATIVE AS ANTITUMOR OR ANTICARCINOGENIC AGENT | BRISTOL-MYERS SQUIBB COMPANY | 2002-09-24 | — | — | US | disclosed |
| US-6011029-A | BENZODIAZEPINE COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-01-04 | — | — | US | disclosed |
| EP-0892797-A1 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997030992-A1 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | BRISTOL-MYERS SQUIBB COMPANY (US) | 1997-08-28 | — | — | WO | disclosed |
| EP-0066303-A1 | 2-Azidomethyl-1,4-benzodiazepines, their salts, process for preparing them and pharmaceutical compositions containing them | Kali-Chemie Pharma GmbH (DE) | 1982-12-08 | — | — | EP | disclosed |
| EP-0054839-A2 | 2-Acylaminomethyl-1,4-benzodiazepines and their salts, methods of preparing them and pharmaceutical compositions containing them | Kali-Chemie Pharma GmbH (DE) | 1982-06-30 | — | — | EP | disclosed |