SCHEMBL6615263

SCHEMBL6615263

C[C@@H]1NC(=O)S[C@H]1c1ccc(Cl)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.47
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
MAPK1 P28482 2/20 0.36
CHRNA7 P36544 1/20 0.36
TNKS2 Q9H2K2 1/20 0.36
KDM4E B2RXH2 3/20 0.35
SLC2A1 P11166 1/20 0.35
RAB9A P51151 1/20 0.34
SLC6A2 P23975 1/20 0.34
SLC6A4 P31645 1/20 0.34
SLC6A3 Q01959 1/20 0.34
NPSR1 Q6W5P4 4/20 0.33
MAPT P10636 3/20 0.33
SMN1; SMN2 Q16637 3/20 0.33
LMNA P02545 3/20 0.33
HTT P42858 3/20 0.33
POLB P06746 2/20 0.33
ALOX12 P18054 2/20 0.33
HPGD P15428 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6615271 1.00 ALDH1A1 (0.47) ALDH1A1MEN1KMT2AMAPK1CHRNA7
SCHEMBL6615267 1.00 ALDH1A1 (0.47) ALDH1A1MEN1KMT2AMAPK1CHRNA7
SCHEMBL10776658 0.85 MAPT (0.43) ALDH1A1MEN1KMT2ATNKS2KDM4E
SCHEMBL10776656 0.85 MAPT (0.43) ALDH1A1MEN1KMT2ATNKS2KDM4E
SCHEMBL10776653 0.85 MAPT (0.43) ALDH1A1MEN1KMT2ATNKS2KDM4E
SCHEMBL11125609 0.79 ALDH1A1 (0.40) ALDH1A1MEN1KMT2ACHRNA7KDM4E
SCHEMBL10619002 0.76 ALDH1A1 (0.49) ALDH1A1MEN1KMT2AMAPK1TNKS2
SCHEMBL10619005 0.76 ALDH1A1 (0.49) ALDH1A1MEN1KMT2AMAPK1TNKS2
SCHEMBL10619009 0.76 ALDH1A1 (0.49) ALDH1A1MEN1KMT2AMAPK1TNKS2
SCHEMBL9211041 0.75 ALDH1A1 (0.37) ALDH1A1MEN1KMT2AMAPK1TNKS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-58029775-A None JP disclosed
JP-57175180-A None JP disclosed
CN-114315752-A Photo-oxidation process of hexythiazox intermediate 江苏禾本生化有限公司 2022-04-12 CN disclosed
EP-1435353-A1 NOVEL HETEROCYCLIC COMPOUND AND ANTI-INFLAMMATORY AGENT NIPPON SODA CO., LTD. (JP) 2004-07-07 EP disclosed
EP-0146748-B1 ORGANOPHOSPHORUS COMPOUND, PROCESS FOR ITS PREPARATION AND INSECTICIDAL, MITICIDAL OR NEMATICIDAL COMPOSITION CONTAINING IT ISHIHARA SANGYO KAISHA, LTD. (JP) 1988-05-04 EP disclosed
US-4590182-A Organophosphorus compound and insecticidal, miticidal or nematicidal composition containing it ISHIHARA SANGYO KAISHA LTD. (JP) 1986-05-20 US disclosed
EP-0146748-A1 Organophosphorus compound, process for its preparation and insecticidal, miticidal or nematicidal composition containing it ISHIHARA SANGYO KAISHA, LTD. (JP) 1985-07-03 EP disclosed
US-4442116-A MITICIDES NIPPON SODA COMPANY, LIMITED (JP) 1984-04-10 US disclosed
US-4431814-A HERBICIDES, MITICIDES, ANTICONVULSANTS NIPPON SODA COMPANY LIMITED (JP) 1984-02-14 US disclosed
JP-S5829775-A TRANS-5-(4-CHLOROPHENYL)-4-METHYL-2-THIAZOLIDONE AND ITS PREPARATION NIPPON SODA CO LTD 1983-02-22 JP disclosed
JP-S57175180-A TRANS-4-METHYL-5-PHENYL-2-THAZOLIDONE AND ITS PREPARATION NIPPON SODA CO LTD 1982-10-28 JP disclosed