Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3692484 | 0.84 | EPHX2 (0.33) | EPHX2LMNA | |
| SCHEMBL4916237 | 0.81 | LMNA (0.34) | LMNA | |
| SCHEMBL4916247 | 0.81 | LMNA (0.34) | LMNA | |
| SCHEMBL2165891 | 0.75 | HCRTR2 (0.36) | — | |
| SCHEMBL4112005 | 0.75 | CYP2C19 (0.32) | LMNA | |
| SCHEMBL322778 | 0.74 | DPP4 (0.34) | LMNA | |
| SCHEMBL16600622 | 0.74 | DPP4 (0.34) | LMNA | |
| SCHEMBL322779 | 0.74 | DPP4 (0.34) | LMNA | |
| SCHEMBL4523902 | 0.74 | DPP4 (0.34) | LMNA | |
| SCHEMBL4108069 | 0.74 | LMNA (0.33) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1404672-A1 | TYROSINE KINASE INHIBITORS | Merck & Co., Inc. (US) | 2004-04-07 | — | — | EP | disclosed |
| WO-2003000687-A1 | TYROSINE KINASE INHIBITORS | MERCK & CO., INC. (US) | 2003-01-03 | — | — | WO | disclosed |