Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | SMO | Q99835 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6635822 | 0.71 | SLC6A4 (0.56) | HTR1ASLC6A4PTGDR2SMOCNR1 | |
| SCHEMBL6614701 | 0.71 | SLC6A4 (0.44) | HTR1ASLC6A4PTGDR2SMO | |
| SCHEMBL6636440 | 0.70 | SMO (0.54) | HTR1ASLC6A4PTGDR2SMOCNR2 | |
| SCHEMBL6637096 | 0.70 | HTR1A (0.53) | HTR1ASLC6A4PTGDR2CNR1CNR2 | |
| SCHEMBL6087735 | 0.69 | SLC6A4 (0.64) | HTR1ASLC6A4PTGDR2SMO | |
| SCHEMBL6087304 | 0.69 | SLC6A4 (0.62) | HTR1ASLC6A4PTGDR2CNR1CNR2 | |
| SCHEMBL6088184 | 0.69 | SLC6A4 (0.62) | HTR1ASLC6A4PTGDR2CNR1CNR2 | |
| SCHEMBL6087259 | 0.69 | SLC6A4 (0.62) | HTR1ASLC6A4PTGDR2CNR1CNR2 | |
| SCHEMBL6087263 | 0.69 | SLC6A4 (0.62) | HTR1ASLC6A4PTGDR2CNR1CNR2 | |
| SCHEMBL6087846 | 0.69 | SLC6A4 (0.62) | HTR1ASLC6A4PTGDR2CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373203-A1 | CYCLOPROPYLINDOLE DERIVATIVES AS SELECTIVE SEROTONIN REUPTAKE INHIBITORS | Bristol-Myers Squibb Company (US) | 2004-01-02 | — | — | EP | claimed |
| WO-2002079152-A1 | CYCLOPROPYLINDOLE DERIVATIVES AS SELECTIVE SEROTONIN REUPTAKE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-10-10 | — | — | WO | claimed |