Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6621856 | 0.87 | CA12 (0.33) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL6616327 | 0.85 | CA12 (0.36) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL6617236 | 0.83 | CA12 (0.36) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL8623804 | 0.82 | KDM6B (0.40) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL6616356 | 0.81 | — | — | |
| SCHEMBL6618067 | 0.81 | NAMPT (0.37) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL6617764 | 0.81 | HCAR3 (0.38) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL8626480 | 0.80 | CA12 (0.36) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL6618114 | 0.80 | UTS2R (0.32) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL6619415 | 0.79 | TAAR1 (0.37) | CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0877748-B1 | PYRIDO-1,2,4-THIADIAZINE AND PYRIDO-1,4-THIAZINE DERIVATIVES, THEIR PREPARATION AND USE | UNIV LIEGE (BE) | 2004-11-03 | — | — | EP | disclosed |
| US-5792764-A | ENDOCRINE DISORDERS ESPECIALLY AS A K(ATP)-CHANNEL MODULATOR | NOVO NORDISK A/S (DK) | 1998-08-11 | — | — | US | disclosed |