Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.45 |
| ▸ | CCR5 | P51681 | 12/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6614098 | 0.95 | CCR5 (0.51) | KMT2AMEN1CXCR3CCR5HTR1A | |
| SCHEMBL6614418 | 0.95 | CCR5 (0.49) | KMT2AMEN1CXCR3CCR5HTR1A | |
| SCHEMBL6613793 | 0.95 | CCR5 (0.52) | KMT2AMEN1CXCR3CCR5HTR1A | |
| SCHEMBL6611637 | 0.93 | CCR5 (0.52) | KMT2AMEN1CXCR3CCR5L3MBTL1 | |
| SCHEMBL6612384 | 0.91 | KMT2A (0.55) | KMT2AMEN1CXCR3CCR5HTR1A | |
| SCHEMBL6012462 | 0.89 | CCR5 (0.52) | KMT2AMEN1CXCR3CCR5HTR1A | |
| SCHEMBL6612178 | 0.88 | MAPT (0.48) | KMT2AMEN1CCR5L3MBTL1 | |
| SCHEMBL6612655 | 0.88 | CCR5 (0.51) | KMT2AMEN1CXCR3CCR5HTR1A | |
| SCHEMBL6612358 | 0.87 | KMT2A (0.46) | KMT2AMEN1HTR1ADRD2DRD4 | |
| SCHEMBL6613915 | 0.86 | CCR5 (0.60) | KMT2ACXCR3CCR5HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1236726-B1 | TRIAZASPIRO 5.5]UNDECANE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO (JP) | 2004-12-01 | — | — | EP | disclosed |
| EP-1236726-A1 | TRIAZASPIRO 5.5]UNDECANE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-09-04 | — | — | EP | disclosed |