Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 10/20 | 0.66 |
| ▸ | MAOA | P21397 | 6/20 | 0.66 |
| ▸ | F10 | P00742 | 8/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | CALML3 | P27482 | 1/20 | 0.51 |
| ▸ | SDHA | P31040 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5763602 | 1.00 | MAOB (0.66) | MAOBMAOAF10LMNAPTGS1 | |
| SCHEMBL6040297 | 0.91 | MAOB (0.66) | MAOBMAOAF10LMNAPTGS1 | |
| SCHEMBL3033109 | 0.91 | MAOB (0.66) | MAOBMAOAF10LMNAPTGS1 | |
| SCHEMBL3038562 | 0.88 | MAOB (0.65) | MAOBMAOAF10LMNAPTGS1 | |
| SCHEMBL4245418 | 0.87 | MAOB (0.61) | MAOBMAOAF10LMNAPTGS1 | |
| SCHEMBL5765886 | 0.85 | MAOA (0.63) | MAOBMAOAF10LMNAPTGS1 | |
| SCHEMBL5512577 | 0.84 | MAOB (0.62) | MAOBMAOAF10LMNAPTGS1 | |
| SCHEMBL4543204 | 0.84 | MAOB (0.62) | MAOBMAOAF10LMNAPTGS1 | |
| SCHEMBL3039286 | 0.83 | MAOA (0.44) | MAOBMAOAF10 | |
| SCHEMBL6614875 | 0.83 | MAOA (0.44) | MAOBMAOAF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451164-A2 | AMIDE DERIVATIVES HAVING IMPROVED SOLUBILITY | PHARMACIA & UPJOHN COMPANY (US) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003006440-A2 | AMIDE-CONTAINING COMPOUND HAVING IMPROVED SOLUBILITY AND METHOD OF IMPROVING THE SOLUBILITY OF AN AMIDE-CONTAINING COMPOUND | PHARMACIA & UPJOHN COMPANY (US) | 2003-01-23 | — | — | WO | disclosed |