Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 20/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 20/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6620065 | 0.91 | HTR1A (0.52) | HTR1ASLC6A4 | |
| SCHEMBL6618081 | 0.89 | HTR1A (0.46) | HTR1ASLC6A4CYP2D6 | |
| SCHEMBL6416617 | 0.88 | HTR1A (0.47) | HTR1ASLC6A4CYP2D6 | |
| SCHEMBL6618111 | 0.88 | HTR1A (0.47) | HTR1ASLC6A4CYP2D6 | |
| SCHEMBL6617323 | 0.87 | HTR1A (0.45) | HTR1ASLC6A4CYP2D6 | |
| SCHEMBL6411434 | 0.87 | HTR1A (0.46) | HTR1ASLC6A4CYP2D6 | |
| SCHEMBL6617273 | 0.86 | HTR1A (0.56) | HTR1ASLC6A4 | |
| SCHEMBL6613854 | 0.84 | HTR1A (0.40) | HTR1ASLC6A4CYP2D6 | |
| SCHEMBL6615662 | 0.84 | HTR1A (0.49) | HTR1ASLC6A4CYP2D6 | |
| SCHEMBL6412020 | 0.83 | HTR1A (0.49) | HTR1ASLC6A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1466901-A1 | SEROTONINE REUPTAKE INHIBITOR | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2004-10-13 | — | — | EP | disclosed |