Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | ATM | Q13315 | 2/20 | 0.55 |
| ▸ | ELANE | P08246 | 4/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GGT1 | P19440 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29376230 | 1.00 | TDP1 (0.55) | TDP1ATMELANEBCHEALDH1A1 | |
| Ethylene SCHEMBL11046108 | 0.98 | TDP1 (0.54) | TDP1ATMELANEBCHEALDH1A1 | |
| SCHEMBL7531230 | 0.92 | TDP1 (0.49) | TDP1ATMELANEBCHEALDH1A1 | |
| Oxirane SCHEMBL3974726 | 0.92 | ATM (0.49) | TDP1ATMELANEBCHEALDH1A1 | |
| SCHEMBL10537603 | 0.90 | TDP1 (0.54) | TDP1ATMELANEBCHEALDH1A1 | |
| SCHEMBL31474595 | 0.89 | TDP1 (0.69) | TDP1ATMELANEBCHEALDH1A1 | |
| SCHEMBL33914 | 0.89 | TDP1 (0.69) | TDP1ATMELANEBCHEALDH1A1 | |
| Benzil SCHEMBL9334075 | 0.88 | ATM (0.56) | TDP1ATMELANEALDH1A1KDM4E | |
| SCHEMBL30603970 | 0.85 | ATM (0.44) | TDP1ATMELANEBCHEALDH1A1 | |
| SCHEMBL9246805 | 0.85 | ATM (0.44) | TDP1ATMELANEBCHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 773 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6352782-B1 | — | — | None | — | — | US | claimed |
| EP-3482740-B1 | DENTAL PHOTOPOLYMERIZABLE COMPOSITION | G C DENTAL IND CORP (JP) | 2024-03-27 | — | — | EP | claimed |
| US-9763753-B2 | Method of dental implant restoration | ZUGA MEDICAL, INC. (US) | 2017-09-19 | — | — | US | claimed |
| US-9566216-B2 | Bone cements containing magnetic calcium phosphate nanoparticles | SOUTHWEST RESEARCH INSTITUTE (US) | 2017-02-14 | — | — | US | claimed |
| US-20150142112-A1 | Bone Cements Containing Magnetic Calcium Phosphate Nanoparticles | SOUTHWEST RESEARCH INSTITUTE | 2015-05-21 | — | — | US | claimed |
| US-20140302459-A1 | Method of dental implant restoration | SICHUAN PROVINCE HEALTH PENSION INDUSTRY EQUITY INVESTMENT FUND LIMITED PARTNERSHIP | 2014-10-09 | — | — | US | claimed |
| US-8367745-B2 | Includes alkaline earth metal oxide as acidity neutralization stabilizer; quick setting, mechanical strength; repairing prosthesis | GC CORPORATION (JP) | 2013-02-05 | — | — | US | claimed |
| EP-2549945-A1 | A METHOD OF DENTAL IMPLANT RESTORATION | Wang, Chan Q. (US) | 2013-01-30 | — | — | EP | claimed |
| WO-2011119131-A1 | A METHOD OF DENTAL IMPLANT RESTORATION | WANG CHAN Q (US) | 2011-09-29 | — | — | WO | claimed |
| EP-1834975-B1 | Thermosetting poly(phenylene ether) | SABIC INNOVATIVE PLASTICS IP (NL) | 2011-05-11 | — | — | EP | claimed |
| US-5416180-A | Fluorine containing (meth)acrylate polymers | MENICON CO., LTD. (JP) | 1995-05-16 | — | — | US | claimed |
| US-5364890-A | (meth)acrylate and a carbodiimide | GC CORPORATION (JP) | 1994-11-15 | — | — | US | claimed |
| EP-0600269-A2 | Soft ocular lens material | Menicon Co., Ltd. (JP) | 1994-06-08 | — | — | EP | claimed |
| US-4698373-A | HARDENABLE ACRYLIC BLENDS CONTAINING SWELLABLE POLYMER PARTICLES; INTERPENETRATING POLYMER NETWORKS; WEAR RESISTANCE | DENTSPLY RESEARCH & DEVELOPMENT CORP. (US) | 1987-10-06 | — | — | US | claimed |
| EP-0014515-B1 | HARDENABLE COMPOSITIONS, PROCESS TO MAKE A SHAPED ARTICLE THEREFROM AND DENTAL APPLIANCE COMPRISING IT | DENTSPLY INTERNATIONAL, INC. (US) | 1984-03-14 | — | — | EP | claimed |
| US-4396476-A | ACRYLIC ESTER HOMO- AND COPOLYMERS; PROSTHETICS; DENISTRY; MOLDING MATERIALS | DENTSPLY RESEARCH & DEVELOPMENT CORPORATION (US) | 1983-08-02 | — | — | US | claimed |
| US-4396377-A | BLEND OF CROSSLINKED POLYMER, POLYMERIZABLE MONOMER AND CROSSLINKING AGENT HARDENED INTO SHAPED BODY | DENTSPLY RESEARCH & DEVELOPMENT CORPORATION (US) | 1983-08-02 | — | — | US | claimed |
| EP-0059525-A2 | Dental compositions | DENTSPLY INTERNATIONAL, INC. (US) | 1982-09-08 | — | — | EP | claimed |
| WO-1982002556-A1 | STABLE ONE ART DENTAL COMPOSITIONS EMPLOYING IPN TECHNOLOGY | DENTSPLY INT INC (US) | 1982-08-05 | — | — | WO | claimed |
| EP-0014515-A2 | Hardenable compositions, process to make a shaped article therefrom and dental appliance comprising it | DENTSPLY INTERNATIONAL, INC. (US) | 1980-08-20 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150142112-A1 | Bone Cements Containing Magnetic Calcium Phosphate Nanoparticles | ACP1, ACP3, BMP2 | TDP1 4556/4885ATM 1386/4885ELANE 3987/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.