Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.35 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLQ | O75417 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GRK2 | P25098 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA4 | P22748 | 2/20 | 0.34 |
| ▸ | CA7 | P43166 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6316589 | 0.90 | KMT2A (0.43) | L3MBTL1KMT2APOLBMAPTKDM4E | |
| SCHEMBL6317244 | 0.84 | KDM4E (0.40) | L3MBTL1KMT2AMAPTKDM4EMEN1 | |
| SCHEMBL6323089 | 0.82 | NPC1 (0.44) | L3MBTL1KMT2APSMB5PSMB8POLB | |
| SCHEMBL6322618 | 0.82 | MAPT (0.47) | L3MBTL1KMT2AMAPTKDM4EMEN1 | |
| SCHEMBL6324110 | 0.81 | MAPT (0.50) | L3MBTL1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL6318971 | 0.81 | TSHR (0.41) | L3MBTL1KMT2APOLBMAPTKDM4E | |
| SCHEMBL6316505 | 0.81 | RAB9A (0.42) | L3MBTL1KMT2APOLBMAPTKDM4E | |
| SCHEMBL6314864 | 0.81 | MAOB (0.45) | L3MBTL1KMT2APOLBMAPTKDM4E | |
| SCHEMBL6316721 | 0.81 | NPC1 (0.55) | L3MBTL1KMT2APSMB5POLBKDM4E | |
| SCHEMBL6617822 | 0.81 | MAOB (0.37) | L3MBTL1KMT2APSMB5MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1435948-A1 | AMINOISOXAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS | Pharmacia Italia S.p.A. (IT) | 2004-07-14 | — | — | EP | claimed |
| WO-2003013517-A1 | AMINOISOXAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS | PHARMACIA ITALIA S.P.A. (IT) | 2003-02-20 | — | — | WO | claimed |
| EP-1435948-A1 | AMINOISOXAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS | Pharmacia Italia S.p.A. (IT) | 2004-07-14 | — | — | EP | disclosed |
| WO-2003013517-A1 | AMINOISOXAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS | PHARMACIA ITALIA S.P.A. (IT) | 2003-02-20 | — | — | WO | disclosed |